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Don’t Take Vitamin Supplements That Your Body Can’t Convert Properly

Methylation defects are relatively new genetic disorders and they are thoroughly being studied and treated around the world. Methylation is a vital part of our bodies’ natural process of detoxification.  Methylation also regulates neurotransmitters and hormones. Individuals with a methylenetetrahydrofolate reductase (MTHFR) mutation have a decreased ability to convert folate--or folic acid--into a usable form. According to research, over half of the population may have an MTHFR gene mutation. There are many variations of this mutation that all point to the same general problem, an incorrect conversion process of folate within the body.  Symptoms of MTHFR mutation can include anxiety, depression, blood sugar problems, autism, chronic fatigue syndrome, heart issues, and more. The problem: metabolizing folic acid Folic acid is the primary supplement for treating problems such as B-vitamin deficiency, reducing the occurrence of neural tube defects and lowering homocysteine levels. Folic acid is so effective that its addition to wheat flour is compulsory in Canada, Australia, the United States, and many other countries. However, proper metabolizing of folic acid is the major problem as most people don’t metabolize it fully, whether from alcohol blocking it, an interfering pharmaceutical medicine or from low MTHFR activity. Folic acid accumulating in the blood can potentially result in dangerous condition referred to as “unmetabolized folic acid” (UMFA).  The solution: L-Methylfolate In addition to limiting your daily intake of fortified wheat flour, you should replace any folic acid supplements with the active form - L-Methylfolate or 5-MTHF. It bypasses MTHFR defects and is helpful in reducing homocysteine concentrations, as well as increasing plasma folate levels.  Furthermore, L-Methylfolate is also absorbed better, does not result in UMFA, and interacts with fewer medications when compared to folic acid.  Supplementing with L-Methylfolate gives one the ability to bypass the entire cycle of folic acid metabolism, which is great news for individuals having an MTHFR mutation. However, one size does not fit all. Sufficient research is required before supplementing for MTHFR defects. Don’t take vitamin supplements that your body can’t convert properly. You will need to learn about them and adjust dosages according to your metabolic changes. There are some key factors to consider before taking vitamin supplements such as 5-MTHF or L-Methylfolate; for example, it may be important for you to find out if you have the mutation and to check your vitamin B12 levels. That’s why proper guidance from a doctor or dietitian who specializes in this field is so important. Methyl-Life.com is helpful in guiding you in this regard. You can find over-the-counter, affordable L-Methylfolate supplement suggestions there, which can help you get your quality of life back. Although most L-Methylfolate supplements are soy, dairy, and gluten-free, it is recommended to always check with your doctor before taking such supplements. Conclusion The treatment of an MTHFR mutation can be complicated. Correctly identifying the type of mutation you have might be a good the first step. Once you have identified the mutation; using vitamin B12 and methylated forms of folate are your primary treatment options. As mentioned above, when it comes to dosing, one size does not fit all. L-Methylfolate amounts can vary from person to person; therefore it is important that you check with your doctor before taking supplements and regularly and carefully monitor your response to supplementation.

Methylation defects are relatively new genetic disorders and they are thoroughly being studied and treated around the world. Methylation is a vital part of our bodies’ natural process of detoxification.  Methylation also regulates neurotransmitters and hormones. Individuals with a methylenetetrahydrofolate reductase (MTHFR) mutation have a decreased ability to convert folate–or folic acid–into a usable form. According to research, over half of the population may have an MTHFR gene mutation. There are many variations of this mutation that all point to the same general problem, an incorrect conversion process of folate within the body.

Symptoms of MTHFR mutation can include anxiety, depression, blood sugar problems, autism, chronic fatigue syndrome, heart issues, and more.

The problem: metabolizing folic acid

Folic acid is the primary supplement for treating problems such as B-vitamin deficiency, reducing the occurrence of neural tube defects and lowering homocysteine levels.

Folic acid is so effective that its addition to wheat flour is compulsory in Canada, Australia, the United States, and many other countries. However, proper metabolizing of folic acid is the major problem as most people don’t metabolize it fully, whether from alcohol blocking it, an interfering pharmaceutical medicine or from low MTHFR activity. Folic acid accumulating in the blood can potentially result in dangerous condition referred to as “unmetabolized folic acid” (UMFA).

The solution: L-Methylfolate

In addition to limiting your daily intake of fortified wheat flour, you should replace any folic acid supplements with the active form – L-Methylfolate or 5-MTHF. It bypasses MTHFR defects and is helpful in reducing homocysteine concentrations, as well as increasing plasma folate levels.

Furthermore, L-Methylfolate is also absorbed better, does not result in UMFA, and interacts with fewer medications when compared to folic acid.

Supplementing with L-Methylfolate gives one the ability to bypass the entire cycle of folic acid metabolism, which is great news for individuals having an MTHFR mutation. However, one size does not fit all. Sufficient research is required before supplementing for MTHFR defects. Don’t take vitamin supplements that your body can’t convert properly. You will need to learn about them and adjust dosages according to your metabolic changes.

There are some key factors to consider before taking vitamin supplements such as 5-MTHF or L-Methylfolate; for example, it may be important for you to find out if you have the mutation and to check your vitamin B12 levels. That’s why proper guidance from a doctor or dietitian who specializes in this field is so important.

Methyl-Life.com is helpful in guiding you in this regard. You can find over-the-counter, affordable L-Methylfolate supplement suggestions there, which can help you get your quality of life back. Although most L-Methylfolate supplements are soy, dairy, and gluten-free, it is recommended to always check with your doctor before taking such supplements.

Conclusion:

The treatment of an MTHFR mutation can be complicated. Correctly identifying the type of mutation you have might be a good the first step. Once you have identified the mutation; using vitamin B12 and methylated forms of folate are your primary treatment options. As mentioned above, when it comes to dosing, one size does not fit all. L-Methylfolate amounts can vary from person to person; therefore it is important that you check with your doctor before taking supplements and regularly and carefully monitor your response to supplementation.

4 Responses to “Don’t Take Vitamin Supplements That Your Body Can’t Convert Properly”

  1. rosabelle says :

    I never thought that MTHFR could affect huge part of the population so this matter should really be addressed so people would be more aware with such condition. Thanks for giving tips about the right way of supplementation. Not everyone knows that taking vitamin supplements could do more harm than good, so we should really be careful when planning for supplementation. Indeed, the advice of the experts could be very helpful.

  2. Monica says :

    Kudos to this author. I found out that the longer I live, the more I appreciate and am amazed by the ability of organisms to heal and stengthen themselves in response to the imposed demands and stimulation provided by normal every day factors we encounter in our environment — food, exercise, social interaction, mental challenges. The factors we evolved to handle quite well, with a bit of wisdom, insight and luck. Thanks

  3. jerome says :

    This is a very well written article. I just read another article on from your website and i gotta say i’m amazed because i didn’t know these things and a lot of people dont know the importance of staying healthy, keeping our body well fed with vitamins and minerals. Because man made products have shown us many times over the years that the products we make sometimes are not the best choice for our bodies.

  4. Riana says :

    Is it hard to figure out if you could use folic acid (if your body is able to metabolize it fully) or should we just go with the L-Methylfolate from the start? I am asking because my doctor has recently told me to take folic acid but no tests were done to see if it’s actually the right choice for me. Where I live, doctors mostly use their intuition which might have worked 20 years ago but today they should rely more on technology. But since we don’t have much technology in my little town…

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