CALMING Your Stress Naturally with the Best Gaba Supplement

  • Provides a sense of CALM
  • Helps manage cortisol
  • Promotes restful sleep
  • Supports cognitive function
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Does anxiousness overwhelm you sometimes? Do you want to manage it with an effective natural remedy instead of taking medications?

Then you're in the right place! For many, getting hijacked & overwhelmed by life's crazy curveballs can sometimes crowd out the ability to function with ease.

If you suffer from an over-active nervous system, you may benefit from our ultra-CALMING product which contains natural forms of Gaba & Saffron as well as NAC, Zinc, Citicoline & Phosphatidylserine - all to support your stress response.

It's been specifically formulated to help both the mind & body settle down almost immediately into a more relaxed state of being. This will allow you to get back to doing what's most important to you. 

Building resilience to stress is crucial for maintaining both mental and physical well-being in today's fast-paced and unpredictable world. Resilience acts as a psychological armor, enabling individuals to navigate challenges with greater ease and adaptability. In the face of stressors, resilient individuals exhibit a capacity to bounce back, learn from adversity, and grow stronger. Methyl-Life’s® product “CALMING for Mind and Body Balance” has been formulated with key nutrients that work together for building and supporting resilience and CALM. It is all natural, free of gluten, dairy, and soy, and does not contain preservatives that could exacerbate symptoms of anxiety. Let’s take a closer look at our formulation.

  • First, we have GABA, which fosters emotional well-being by slowing down neurotransmitter hyperactivity which benefits individuals in managing and regulating their responses to stress.
  • Next, we have Saffron, a nutrient that not only comes from a beautiful flower, but has been shown to provide positive effects on MOOD and SLEEP by supporting healthy levels of norepinephrine, dopamine, and serotonin while lowering high levels of homocysteine.
  • The wonder nutrient NAC is known for its supportive role in reducing the risk of chronic psychological issues such as anxiety and depression by modulating the release of dopamine, it’s anti-inflammatory, promotes detoxification, and functions as a powerful antioxidant through stimulating the synthesis and increase of intracellular glutathione.
  • Phosphatidylserine is pivotal in enhancing cognitive function, enabling better problem-solving and decision-making under pressure, in addition to helping regulate cortisol levels (the hormone that produces the “fight or flight” response).
  • Other accompanying nutrients (Zinc and Citicoline) work in supporting healthy cognitive function by reducing inflammation which promotes healthy brain cell membranes, synapses, and the ability to focus.

You may find our formula helps improve your sleep - especially if you take it along with an absorptive form of magnesium in the evening.

CALMING for Mind and Body Balance can contribute to a healthier and more resilient lifestyle by reducing symptoms of stress, which is associated with detrimental effects on the body, including depression, cardiovascular problems and weakened immune function. By building resilience through strategies like supportive nutrition, mindfulness, positive thinking, and social support you can mitigate some of these negative impacts.

CALMING for Mind and Body Balance empowers individuals to face life's inevitable stressors with grace and fortitude, ultimately leading to a more fulfilling, CALM, and balanced life.

For best results always consult your Healthcare Practitioner when you add new nutrients to your routine.

In the absence of directions from your Healthcare Specialist, consider taking one capsule when you are especially activated and wish to "CALM down" quickly. Consider taking an additional capsule if you gain some relief from a single capsule, but feel a second one may be beneficial.

Be aware that the product could make some folks sleepy. 

SUGGESTED USE: Consult with your healthcare practitioner before using this product. 

Serving Size: 1 Capsule
60 servings per container Amount per Serving % Daily Value
Zinc 11 mg 100%
N-Acetyl L-Cysteine (NAC) - 98.5% 255 mg  
Gamma Amino Butyric Acid 72 mg   
Citicoline 45 mg   
Phosphatidylserine 45 mg   
Saffron  ( (Stigma) )
 (Crocus sativus) Extract 3% Crocins
10 mg *   

   *  Daily value not established

OTHER INGREDIENTS: capsule (water, hypromellose). 

Product Does NOT Contain: wheat, gluten, soy, dairy, tree nuts, animal products, GMO’s. No artificial ingredients or colorings.

Citicoline: pharmacological and clinical review, 2022 update (

Application of Citicoline in Neurological Disorders: A Systematic Review (

Methylfolate 15 How does Gaba help with stress or anxiety?

GABA is a neurotransmitter that plays a crucial role in regulating mood and reducing anxiety by improving the gaba/glutamate balance. Supplementation with GABA may help in calming the nervous system and therefore reducing stress and anxiety levels. Individuals with MTHFR mutations may have impaired neurotransmitter function, including GABA.

Methylfolate 15 How does Saffron help with stress or anxiety?

Saffron contains compounds like safranal and crocin, which have been shown to have antidepressant and anxiolytic effects. These compounds may modulate neurotransmitter levels in the brain, including serotonin, dopamine and GABA, which could help alleviate stress and improve mood.

Methylfolate 15 What does Zinc have to do with mental health?

Zinc is an essential mineral that plays a role in numerous biochemical processes in the body, including neurotransmitter function and immune system regulation.
Zinc deficiency is associated with increased stress, anxiety, and depression.
Individuals with MTHFR mutations may have impaired absorption or utilization of zinc, leading to deficiency.
Supplementation with zinc may help correct deficiencies and support overall mental well-being.

Methylfolate 15 How does NAC protect cognition and improve mental health?

NAC has the capability of modulating neurological pathways like glutamate dysregulation, oxidative stress, and inflammation - all of which can affect how the brain functions. N-acetylcysteine is being explored and has been used as an added therapy for some psychiatric conditions. NAC is a precursor to glutathione, the body's most powerful antioxidant.
MTHFR mutations can lead to reduced glutathione levels, which may result in oxidative stress and inflammation.
NAC can replenish intracellular glutathione levels which support methylation and detoxification. NAC can help reduce oxidative stress and inflammation, which are often elevated in individuals with MTHFR mutations and may contribute to stress and anxiety.

Methylfolate 15 Can Phosphatidylserine improve my brain function?

Phosphatidylserine is a phospholipid that is a component of cell membranes, particularly in brain cells.
It plays a role in neurotransmitter release and receptor function, including those involved in stress response and mood regulation.
Supplementation with phosphatidylserine may help support cognitive function, reduce cortisol levels, and alleviate stress.

Methylfolate 15 How does Citicoline help with brain health?

Citicoline is a nutrient that is foundational for brain health and neurotransmitter synthesis. It plays a role in the protection and health of brain cells. A systematic review found that citicoline has a positive impact on learning and cognition (it improves memory and attention) among the healthy population. In that same study, it was also determined that citicoline could be considered an important nutrient for treating many neurological diseases.
Application of Citicoline in Neurological Disorders: A Systematic Review (

Please Note

Before purchasing any of our products, Methyl-Life® recommends that you talk with a healthcare professional if you have any questions. Methyl-Life® cannot be held liable for adverse reactions or negative side effects that you think are the result of one of our products.

If you have not used Methyl-Life® products before, please consider ordering one bottle to start before making larger orders. We also recommend you read through our dosage and methylation protocol pages and consider starting with a lower dose product to ensure you tolerate the ingredients well before increasing your strength to a higher dose product.

It is also important to speak with your healthcare professional before purchasing. Methyl-Life® prefers not to accept returns for large orders. If you return three unopened bottles from a 4-pack purchase, you will receive a full refund minus the cost of one bottle charged at full price.

Within 45 days of your order, you can return any unopened item shipped to you by Methyl-Life® (as long as all seals are intact). Just let us know you plan to return the product by emailing us at: or using the Contact Us form (please include the tracking information so we can be on the lookout for the package).

It will be your responsibility and cost to ensure the return parcel gets to Methyl-Life® (ship to: P.O. Box 33606, Seattle, WA 98133). We suggest you get a tracking number and consider insuring the package. After we receive your returned item, we will process your full refund within 10 business days and send you an email indicating your refund has been complete. Be aware that depending upon your institution, this may not be reflected in your account status for a few days.

If you have received the wrong item or your product has been damaged or is somehow defective, please email us at: with detailed information or use the Contact Us form and our Customer Service Manager will address your concern(s) right away. Please do not throw any items away unless or until you are directed to do so.



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