Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables – Methyl-Life Supplements
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables
Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables

Active Ingredients - (90 Chewables)  
Folate   7,500 mcg (as Magnafolate-C®)  
Hydroxocobalamin  1,500 mcg
Adenosylcobalamin  1,000 mcg 
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Methylfolate 7.5+ - L-Methylfolate + Active B12s - 90 Chewables

Regular price $62.00 Sale price $54.00
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Methyl-Life products contain the most bioactive nutrient form of folate available today, L-Methylfolate (often denoted as (6S)-5-Methyltetrahydrofolate , L-MTHF, L-5-MTHF). This is the ‘already converted’ form of the vitamin that is immediately ready for the body’s cells to use directly. It’s the only form of folate which crosses the blood-brain barrier.  

Every serving in Methyl-Life’s Methylfolate 7.5+ product contains a high dose (7.5 mg) of L-Methylfolate as internationally-patented Magnafolate® and 2.5 mg of Active B12 (as both Hydroxocobalamin and Adenosylcobalamin).  We specifically deliver this power-packed combination in a tasty, chewable tablet that can sit under the tongue for maximum B12 absorption.

Methylfolate 7.5+ was formulated, especially for the people with genetic (MTHFR, MTR, MTRR) variants or dietary need. It was designed specifically to bypass genetic challenges and optimize the body’s methylation process. This means you may have more energy and motivation, get improved protection against toxins, and just plain feel better. High doses of L-Methylfolate are designed to support optimal neurotransmitter balance and function which may positively affect mood.  It can also convert homocysteine into methionine which can support cardiovascular health. L-Methylfolate can boost glutathione levels in the body (and glutathione is a great ally when it comes to detoxification, it’s your body’s strongest antioxidant).  Talk to your doctor to determine, if taking high doses of L-Methylfolate is right for you.

Methyl-Life is honored to have been the first company in the USA to offer this uniquely pure and superior form of L-Methylfolate, (Magnafolate®), to our customers for over 5 years now.  And we remain proud that we can offer such an exceptional product line at such an affordable price point (because as a family-owned company, we know this is important to you).  No other competitor sells a comparable product for less.  We go above and beyond with our quality standards by investing in additional 3-year stability studies and third party lab testing to ensure our final products are the very best you can buy.

WARNING - How much is right for you to take? Talk to your doctor about what’s best for you. Before you purchase, check out our dosage information page to learn more about what some doctors recommend. Or check out our dosage video.

We spent a great deal of time on our formulations and believe they are optimal for three key reasons:

  • Superior formula - We chose the chewable form specifically to ensure the best absorption of the ingredients, it's a known fact that B12 does not absorb well through the stomach lining, but much better through the mucosa (or under the tongue - so hold the pieces of the tablet in your mouth until they dissolve).
  • Perfect dosage - Our formulation allows you to take the higher doses of Methylfolate you need with less pills per day, and more cost effectively. It also allows for more flexible dosing, for example, one family member may only need one pill per day and another may require 2 pills per day.
  • Ideal formula - We included the primary B vitamins needed to promote methylation in individuals with an MTHFR gene defect (Folate as Methylfolate and B12 as Hydroxocobalamin & Adenosylcobalamin) so you can have an optimum daily dose of these essential bioactive Bs in one easy tablet!
SUGGESTED USE: Ask your doctor. Visit
Bite tablet into pieces, and hold under tongue or between gum and cheek until they dissolve. Great for teeth, not for animals (contains xylitol).
Serving Size: 1 Chewable Tablet
Amount per Serving
% Daily Value
7,500 mcg
(from (6S)-5-Methyltetrahydrofolate, Calcium - as Magnafolate-C®)
Vitamin B12
2,500 mcg Total
(as Hydroxocobalamin - 1,500 mcg)
(as Adenosylcobalamin - 1,000 mcg)
OTHER INGREDIENTS: xylitol (from hardwoods), microcrystalline cellulose, stearic acid, silicon dioxide, less than 1% dextrose, peppermint oil, natural FEMA GRAS aromatics.
What is the right dosage for me? Check out our dosage information page to learn more about what some doctors recommend. Or check out our dosage video.
Is Methylfolate the only thing I should take if I have an MTHFR gene mutation?
No, actually our recommendation is to heavily consider following Dr. Neil Rawlins’ full supplement protocol. You can learn more about his protocol by watching parts 3 & 4 of his video seminar.

What do doctors have to say about MTHFR and how to treat it?
Is L-Methylfolate and (6S)-5-Methyltetrahydrofolate, Calcium or (6S)-5-Methylfolate, glucosamine salt the same thing?
Basically, yes. In the chemistry world, L stands for the “Left” isomer, which is the same as the “(6S)” isomer - the terms are synonyms (and this naming convention is used interchangeably by various companies in the industry). In the case of methylfolate, that L or (6S) isomer is the active isomer of 5-MTHF that the body can actually use. The L-5-MTHF [or (6S)-5-MTHF] enzyme is bound to a salt molecule and in the case of one ingredient (Magnafolate-C®), it’s bound to a calcium salt molecule for delivery to the body (this is the pharma-identical version), and in the case of another ingredient (Quatrefolic®), it’s bound to a glucosamine salt molecule for delivery to the body (this is derived from shellfish, so be aware of potential reactions). To learn more about the different types of methylfolate, its history, potency levels and stability details, visit our Methylfolate Types page.

Please Note

Before purchasing any of our products, Methyl-Life recommends that you talk with a healthcare professional if you have any questions. Methyl-Life cannot be held liable for adverse reactions or negative side effects that you think are the result of one of our products.

If you have not used Methyl-Life products before, please consider ordering one bottle to start before making larger orders. We also recommend you read through our dosage and methylation protocol pages and consider starting with a lower dose product to ensure you tolerate the ingredients well before increasing your strength to a higher dose product.

It is also important to speak with your healthcare professional before purchasing. Methyl-Life prefers not to accept returns for large orders. If you return three unopened bottles from a 4-pack purchase, you will receive a full refund minus the cost of one bottle charged at full price.

Within 45 days of your order, you can return any unopened item shipped to you by Methyl-Life (as long as all seals are intact). Just let us know you plan to return the product by emailing us using the Contact Us form (please include the tracking information so we can be on the lookout for the package).

It will be your responsibility and cost to ensure the return parcel gets to Methyl-Life (ship to: P.O. Box 1484, Renton, WA 98057). We suggest you get a tracking number and consider insuring the package. After we receive your returned item, we will process your full refund within 10 business days and send you an email indicating your refund has been complete. Be aware that depending upon your institution, this may not be reflected in your account status for a few days.

If you have received the wrong item or your product has been damaged or is somehow defective, please email us with detailed information using the Contact us form and our Customer Service Manager will address your concern right away. Please do not throw any items away unless or until you are directed to do so.



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