L-Methylfolate

Name: L-Methylfolate
Brand: Methyl-Life
Rating: 4.9 (239 reviews)

Methyl-Life®’s L-Methylfolate supplements deliver the purest, most potent OTC L-Methylfolate available, supporting mood, heart health, pregnancy, and mental clarity. They're ideal if you need high-dose L-Methylfolate based on genetic testing or medical advice and are already getting active B-12 from another source.

Potent, targeted methylation support for intensive health needs

Higher-Dose L-Methylfolate Therapeutic Formulations

High-potency products containing 15 mg or more of L-Methylfolate, often combined with methylated B12. These are designed for individuals with significant methylation requirements, confirmed by genetic testing or therapeutic recommendations, addressing conditions associated with folate deficiency.

L Methylfolate 15 mg - A Mood-Boosting Supplement

Professional Strength - Ask Your Doctor
High-Dose L Methylfolate 15 Mg for Natural Mood Support²
3rd-Party Tested for Purity, Potency & Safety

L Methylfolate 15mg + Vitamin B12 with Methyl

Bioactive L Methylfolate 15 Mg with Mood-Boosting Power²
Vitamin B12 with Methyl for Neurotransmitter Synthesis¹⁰
3rd-Party Tested for Purity, Potency & Safety

Balanced dosing for elevated support of mood, cognition, and cardiovascular health

Medium-Dose L-Methylfolate Formulations

Supplements offering medium doses of L-Methylfolate (typically 7.5–10 mg), providing enhanced nutritional support for users with moderate methylation demands, mild genetic variants, or those transitioning to higher therapeutic dosing. Ideal for those needing stronger support than foundational levels.

L Methylfolate 7.5 mg + Vitamin B12 Tablets

Therapeutic, Professional Strength L Methylfolate
Bioactive, Sublingual Vitamin B12 Tablets
3rd-Party Tested for Purity, Potency & Safety

Methylfolate Supplement 10 mg

Supports Brain⁴ & Cardiovascular Function⁵
Bioactive L-Methylfolate For Healthy DNA¹⁰
3rd-Party Tested For Purity, Potency & Safety

Essential active folate for baseline support of methylation and wellness

Foundational & Low-Dose L-Methylfolate Supplements

Moderate and lower-dose L-Methylfolate formulations designed for daily nutritional support, mood regulation, cardiovascular health, and maintenance of methylation balance. Suitable for those beginning supplementation or requiring gentle folate support.

L Methylfolate Supplement 2.5 mg

Supports Healthy DNA Synthesis¹⁰
Promotes Balanced Homocysteine Levels⁹
3rd-Party Tested for Purity, Potency & Safety

5 Methylfolate: 5-mthf L-Methylfolate 5 mg

Bioactive 5 Methylfolate That Crosses Blood-Brain Barrier³
Supports Cardiovascular Function⁵ & Brain Health⁴
3rd-Party Tested for Purity, Potency & Safety

Methyl-Life® L-Methylfolate Supplements: Pure, Potent Active Folate for Targeted Methylation and Health Optimization

Methyl-Life® offers a premium selection of L-Methylfolate supplements that provide the purest and most potent active folate forms on the market, meeting USP standards for quality and efficacy. L-Methylfolate is the bioactive form of folate that bypasses common metabolic bottlenecks and genetic variants such as MTHFR mutations, making it essential for supporting numerous critical physiological processes, including mood regulation, cardiovascular health, cognitive function, pregnancy-related fetal development, and overall mental clarity.

These products are designed for individuals who require high doses of active L-Methylfolate, often guided by genetic testing or professional recommendations, and are typically combined with active forms of vitamin B12 either within the same formulation or through separate supplementation.

Why L-Methylfolate?

Unlike synthetic folic acid, L-Methylfolate is directly usable by the body without conversion, making it highly effective for promoting essential biochemical pathways:

DNA and RNA synthesis – Vital for cell division, repair, and fetal development.
Neurotransmitter synthesis – Includes serotonin, dopamine, and more, supporting mood balance and brain function.
Homocysteine metabolism – Helps maintain healthy cardiovascular function by converting homocysteine to methionine