Mood, Energy + Methylation Support Bundle

Methylated B Vitamins: MTHFR Folate, B12 Methylcobalamin & Cofactors for Mood Support

Methylated B Vitamins 3-Product Bundle, Pro-Strength to Enhance Mood. MTHFR Folate 10mg, B12 Methylcobalamin, & Cofactors for optimal absorption & methylation support.

  • MTHFR Folate for Max Absorption & Improving Mood
  • B12 Methylcobalamin Bioactive Sublingual for Blood Health
  • 3rd-Party Tested for Purity, Potency & Safety
  • 90 Count, Non-GMO, Gluten-Free

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Get Methyl-Life’s® foundational bundle - 3 solid products to keep your mood elevated and your biopathways methylated.

This comprehensive starting package contains the bioactive nutrients:

  • The purest L-Methylfolate (as shown in a recent study)
  • All 3 active forms of B12 (as Methylcobalamin, Hydroxy B12, & Adenosylcobalamin)
  • The optimal methylation-supporting multivitamin

How much should you take?

Every individual’s needs are different. Always consult your healthcare provider to determine the right dose for your specific needs.

Doctor-guided support

Visit our Dosage Information and Methylation Protocol pages to learn what some practitioners recommend, including step-by-step guidance for individuals with MTHFR gene variants.

Splitting tablets

Each chewable tablet is scored and can be split in half without a pill cutter. For best results, place your thumbs along the scored line with the tablet facing away from you, and press outward to snap. Watch the full demonstration in our tablet-splitting video.

Additional considerations

This supplement is designed to be taken daily or as recommended by your healthcare practitioner. In the absence of directions from your Healthcare Specialist, consider taking one to two tablets after meals. If you gain some relief from a single tablet, consider taking an additional tablet if you feel a second one may be beneficial.

Check out the details below regarding each specific product included in the bundle using the links below:

Methylated B Vitamins: MTHFR Folate, B12 Methylcobalamin & Cofactors for Mood Support
$129

Traceable Ingredients You Can Trust

Every ingredient is sourced for purity, backed by clinical evidence, and rigorously tested for safety and bioavailability. Because in supplements, not all ingredients are created equal — and your body deserves only the most effective forms.

Methyl-Life® Methylated B Vitamins: MTHFR Folate, B12 Methylcobalamin & Cofactors for Mood Support contains no unnecessary excipients, synthetic colors, artificial preservatives, or common allergens. It is 100% free from gluten, soy, dairy, GMOs, animal-derived ingredients, and the EU’s top 14 allergens.

Every batch is third-party tested for purity, potency, and safety, manufactured in NSF-certified, cGMP-compliant facilities, and rigorously evaluated to ensure you’re getting clean, clinical-grade nutrients — nothing more, nothing less.

EU’s top 14 allergens

  • Cereals containing gluten - wheat (such as spelt and khorasan wheat), rye, barley, oats. Note: The cereal name, e.g., 'wheat', must be declared and highlighted, not 'gluten'.
  • Crustaceans, e.g., crabs, prawns, lobsters
  • Eggs
  • Fish
  • Peanuts
  • Soybeans
  • Milk
  • Nuts (almonds, hazelnuts, walnuts, cashews, pecan nuts, brazil nuts, pistachio nuts, macadamia/Queensland nut). Note: The name of the nut, e.g., 'almond', must be declared and highlighted, not 'nuts'.
  • Celery
  • Mustard
  • Sesame seeds
  • Sulphur dioxide and sulphites (at concentrations of more than 10 mg/kg or 10 mg/L in terms of total sulphur dioxide) – used as a preservative
  • Lupin 
  • Molluscs, e.g., mussels, oysters, squid, snails

Frequently Asked Question

Check out our Dosage page to learn what some doctors are saying. And consider reviewing our Methylation Protocol page as one example of how someone could start taking the active methylation nutrients.
The Methyl-Life® Mood Support Bundle is a foundational package consisting of three solid products aimed at maintaining elevated mood and supporting methyl pathways within the body.
Basically, yes. In the chemistry world, L stands for the “Left” isomer, which is the same as the “(6S)” isomer – the terms are synonyms (and this naming convention is used interchangeably by various companies in the industry). In the case of methylfolate, that L or (6S) isomer is the active isomer of 5-MTHF that the body can actually use. To learn more about the different types of methylfolate, its history, potency levels and stability details, and to see how our L-Methylfolate proves to be the purest on the planet, visit our Methylfolate Types page.
Dr. Amy Yasko and Nutritionist Cynthia Smith both suggest you can consider taking low dose lithium orotate (Cynthia Smith suggests approximately 4.6 mg pulsed a couple times a week before adding the B12 form in that’s most likely best for you).
The Non-Methylated Multivitamin not only supports methylation pathways but also provides cognitive and energy-promoting nutrients essential for maintaining a positive mood and overall well-being.
No, actually our recommendation is to heavily consider following Dr. Neil Rawlins’ full supplement protocol. You can learn more about his protocol by watching his video seminar.

You can also download one of specific Methylation Protocols which guide you through the beginning nutrients to start. We recommend starting low and slowly titrating up to a dose that works well for you long term.

You'll find our MTHFR Newbies page is very helpful as well. It's got some great tips for folks who haven't done much study on what to do if you have an MTHFR variant.
Methylfolate is essential for neurotransmitter synthesis and methylation processes within the brain, which can directly impact mood regulation. The 10 mg dosage in this bundle provides robust support for maintaining elevated mood levels.
The most important thing to realize is that blood tests for B12 are highly inaccurate at detecting actual cellular levels of B12 (meaning the B12 that’s available for the cells to use). Studies have shown that people can have high or normal B12 levels in the blood and actually show virtually no B12 in the spinal fluid, meaning the B12 is not being transported from the blood stream into the cells where it should be absorbed and used.
B12 Complete offers a unique combination of three active forms of B12, each playing a crucial role in energy metabolism and neurological function. This potent blend supports overall mood and vitality.
Follow the recommended dosage instructions provided with each product, as they may vary based on individual needs. The supplements in this bundle are designed for daily consumption and can be taken with or without food.