Mood, Energy + Methylation Support Bundle

Methylated B Vitamins: MTHFR Folate, B12 Methylcobalamin & Cofactors for Mood Support

Regular price $129.00

Methylated B Vitamins 3-Product Bundle, Pro-Strength to Enhance Mood. MTHFR Folate 10mg, B12 Methylcobalamin, & Cofactors for optimal absorption & methylation support.

  • MTHFR Folate for Max Absorption & Improving Mood
  • B12 Methylcobalamin Bioactive Sublingual for Blood Health
  • 3rd-Party Tested for Purity, Potency & Safety
  • 90 Count, Non-GMO, Gluten-Free

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Get Methyl-Life’s® foundational bundle - 3 solid products to keep your mood elevated and your biopathways methylated.

This comprehensive starting package contains the bioactive nutrients:

  • The purest L-Methylfolate (as shown in a recent study)
  • All 3 active forms of B12 (as Methylcobalamin, Hydroxy B12, & Adenosylcobalamin)
  • The optimal methylation-supporting multivitamin
Supplement Facts
Serving Size: 1 Chewable Tablet
Servings Per Container: 90
Amount Per Serving Daily Value
Vitamin B12 5,000 mcg
(as Methylcobalamin 50% [2,500 mcg], Hydroxy B12 25% [1,250 mcg], Adenosylcobalamin 25% [1,250 mcg])
208,333%

*DFE = Dietary Folate Equivalents.

Other Ingredients

Xylitol (Xylisorb®), microcrystalline cellulose (Microcel®), stearic acid, silicon dioxide, natural mint flavoring. Not a significant source of sugars.

Allergen & Safety Information

  • Does not contain: wheat, gluten, soy, dairy, tree nuts, animal products, or GMOs
  • No artificial ingredients or colorings
  • Sweetened with xylitol — do not give to pets

Suggested Use

Take 1 chewable tablet daily, or as directed by your healthcare practitioner.
May be chewed, dissolved in the mouth or swallowed.

Supplement Facts
Serving Size: 1 Chewable Tablet
Servings Per Container: 90 servings per container
Amount Per Serving Daily Value
Folate 17,000 mcg DFE
(10 mg L-Methylfolate from 14 mg of Cerebrofolate®)
4,250%
Supplement Facts
Serving Size: 2 Veggie Capsules
Servings Per Container: 45 servings per container
Amount Per Serving Daily Value
Vitamin A 300 mcg RAE (1,000 IU)
(as Retinyl Palmitate)
33%
Vitamin D 50 mcg (2,000 IU)
(as Cholecalciferol [D3])
250%
Vitamin E 12 mg
(as d-α-Tocopheryl Acid Succinate)
80%
Thiamin 1 mg
(Vitamin B1) (as Thiamin HCI)
83%
Vitamin B2 8 mg
(as Riboflavin 5 Sodium Phosphate)
615%
Niacin 20 mg NE
125%
Vitamin B6 5 mg
(as Pyridoxal 5 Phosphate)
294%
Biotin 60 mcg
200%
Pantothenic Acid 22 mg
(as B5 - D-Calcium Pantothenate)
440%
Iodine 100 mcg
(as Potassium Iodide)
67%
Zinc 15 mg
(as sustained release micropellet)
136%
Selenium 100 mcg
(as Sucrosomial Selenium (UltraSel®))
182%
Manganese 3 mg
(Manganese Bisglycinate Citrate)
130%
Molybdenum 35 mcg
(Molybdenum Glycinate (ALBION))
78%
Artichoke 50 mg
(Leaf) Extract 5% Cynarin)
Citicoline Sodium 50 mg
Ubiquinol 10 mg
(CoQ10 Reduced Form)
Phosphatidylserine 50 mg
(Sunflower - Helianthus annuus)
Milk Thistle 50 mg
((Seed) Extract 80% Silymarin)
Trimethylglycine 50 mg
(TMG)
Pantethine 50% 14 mg
Para-Aminobenzoic Acid 10 mg
(PABA) (Vitamin B10)
Benfotiamine 20 mg
(Fat Soluble Vitamin B1)
NADH 1 mg
(Microencapulated NADH)
Vitamin K2 80 mcg
(as Menaquinone-7)
† Daily Value not established.

How much should you take?

Every individual’s needs are different. Always consult your healthcare provider to determine the right dose for your specific needs.

Doctor-guided support

Visit our Dosage Information and Methylation Protocol pages to learn what some practitioners recommend, including step-by-step guidance for individuals with MTHFR gene variants.

Splitting tablets

Each chewable tablet is scored and can be split in half without a pill cutter. For best results, place your thumbs along the scored line with the tablet facing away from you, and press outward to snap. Watch the full demonstration in our tablet-splitting video.

Additional considerations

This supplement is designed to be taken daily or as recommended by your healthcare practitioner. In the absence of directions from your Healthcare Specialist, consider taking one to two tablets after meals. If you gain some relief from a single tablet, consider taking an additional tablet if you feel a second one may be beneficial.

Check out the details below regarding each specific product included in the bundle using the links below:

Methylated B Vitamins: MTHFR Folate, B12 Methylcobalamin & Cofactors for Mood Support
$129

Traceable Ingredients You Can Trust

Every ingredient is sourced for purity, backed by clinical evidence, and rigorously tested for safety and bioavailability. Because in supplements, not all ingredients are created equal — and your body deserves only the most effective forms.

Methyl-Life® Methylated B Vitamins: MTHFR Folate, B12 Methylcobalamin & Cofactors for Mood Support contains no unnecessary excipients, synthetic colors, artificial preservatives, or common allergens. It is 100% free from gluten, soy, dairy, GMOs, animal-derived ingredients, and the EU’s top 14 allergens.

Every batch is third-party tested for purity, potency, and safety, manufactured in NSF-certified, cGMP-compliant facilities, and rigorously evaluated to ensure you’re getting clean, clinical-grade nutrients — nothing more, nothing less.

EU’s top 14 allergens

  • Cereals containing gluten - wheat (such as spelt and khorasan wheat), rye, barley, oats. Note: The cereal name, e.g., 'wheat', must be declared and highlighted, not 'gluten'.
  • Crustaceans, e.g., crabs, prawns, lobsters
  • Eggs
  • Fish
  • Peanuts
  • Soybeans
  • Milk
  • Nuts (almonds, hazelnuts, walnuts, cashews, pecan nuts, brazil nuts, pistachio nuts, macadamia/Queensland nut). Note: The name of the nut, e.g., 'almond', must be declared and highlighted, not 'nuts'.
  • Celery
  • Mustard
  • Sesame seeds
  • Sulphur dioxide and sulphites (at concentrations of more than 10 mg/kg or 10 mg/L in terms of total sulphur dioxide) – used as a preservative
  • Lupin 
  • Molluscs, e.g., mussels, oysters, squid, snails

Frequently Asked Question

What is the right dosage for me?
Check out our Dosage page to learn what some doctors are saying. And consider reviewing our Methylation Protocol page as one example of how someone could start taking the active methylation nutrients.
What is the Methyl-Life® Mood Support Bundle?
The Methyl-Life® Mood Support Bundle is a foundational package consisting of three solid products aimed at maintaining elevated mood and supporting methyl pathways within the body.
Is L-Methylfolate and (6S)-5-Methyltetrahydrofolate, Calcium the same thing?
Basically, yes. In the chemistry world, L stands for the “Left” isomer, which is the same as the “(6S)” isomer – the terms are synonyms (and this naming convention is used interchangeably by various companies in the industry). In the case of methylfolate, that L or (6S) isomer is the active isomer of 5-MTHF that the body can actually use. To learn more about the different types of methylfolate, its history, potency levels and stability details, and to see how our L-Methylfolate proves to be the purest on the planet, visit our Methylfolate Types page.
What can you do if you have high B12 blood test results?
Dr. Amy Yasko and Nutritionist Cynthia Smith both suggest you can consider taking low dose lithium orotate (Cynthia Smith suggests approximately 4.6 mg pulsed a couple times a week before adding the B12 form in that’s most likely best for you).
How does the Non-Methylated Multivitamin contribute to mood support?
The Non-Methylated Multivitamin not only supports methylation pathways but also provides cognitive and energy-promoting nutrients essential for maintaining a positive mood and overall well-being.
Is Methylfolate the only thing I should take if I have an MTHFR gene mutation?
No, actually our recommendation is to heavily consider following Dr. Neil Rawlins’ full supplement protocol. You can learn more about his protocol by watching his video seminar.

You can also download one of specific Methylation Protocols which guide you through the beginning nutrients to start. We recommend starting low and slowly titrating up to a dose that works well for you long term.

You'll find our MTHFR Newbies page is very helpful as well. It's got some great tips for folks who haven't done much study on what to do if you have an MTHFR variant.
How does Methylfolate 10 benefit mood support?
Methylfolate is essential for neurotransmitter synthesis and methylation processes within the brain, which can directly impact mood regulation. The 10 mg dosage in this bundle provides robust support for maintaining elevated mood levels.
What if my blood serum B12 level test comes back as high, does that mean I don’t need B12?
The most important thing to realize is that blood tests for B12 are highly inaccurate at detecting actual cellular levels of B12 (meaning the B12 that’s available for the cells to use). Studies have shown that people can have high or normal B12 levels in the blood and actually show virtually no B12 in the spinal fluid, meaning the B12 is not being transported from the blood stream into the cells where it should be absorbed and used.
What are the advantages of B12 Complete in the bundle?
B12 Complete offers a unique combination of three active forms of B12, each playing a crucial role in energy metabolism and neurological function. This potent blend supports overall mood and vitality.
How should the products in the bundle be consumed?
Follow the recommended dosage instructions provided with each product, as they may vary based on individual needs. The supplements in this bundle are designed for daily consumption and can be taken with or without food.