Chewable Digestive Enzymes
Chewable Digestive Enzymes
Chewable Digestive Enzymes
Chewable Digestive Enzymes
Chewable Digestive Enzymes
Chewable Digestive Enzymes
Chewable Digestive Enzymes
Gluten-Free Dairy-Free No Artificial Additives Fish/Shellfish-Free Vegan-Friendly Non-GMO BPA-Free Top 14 Allergen-Free
Manufactured: March 2025

Methyl-Life® supplements typically retain their potency for 2-3 years.  They should be stored in their original, tightly sealed containers in a cool, dry place away from heat, moisture, and direct sunlight.
Supports Digestive Comfort + Nutrient Absorption

Chewable Digestive Enzymes

$46.00

Methyl-Life® Chewable Digestive Enzymes is a comprehensive, broad-spectrum enzyme formula in a clean, mint-flavored chewable tablet. It supports the efficient digestion of proteins, carbohydrates, fats, dairy sugars and plant fibers - helping ease occasional indigestion, gas and bloating while supporting nutrient absorption from food.
  • Broad-spectrum enzyme system targeting protein, carb, fat, dairy sugar and plant fiber breakdown
  • 3rd-Party Tested for purity, potency and safety

Free Shipping on Orders Over $100

Your body naturally produces  a wide range of digestive enzymes to break down the foods you eat and absorb nutrients efficiently. However, enzyme production can weaken over time,- which may lead to occasional bloating, fullness, gas, or other digestive discomfort.

This chewable formula provides natural digestive enzymes involved in the breakdown of starch, protein, fats and fiber. Taken after eating, it helps support smoother digestion and efficient nutrient breakdown without harsh ingredients or unnecessary additives.

Proteins (meat, dairy, plant proteins)

A blend of protease enzymes helps break down large proteins into bioavailable  amino acids.  It also includes Dipeptidyl-peptidase IV (DPP-IV) to help degrade proline-rich peptides (such as those present in gliadin) that many people struggle to digest. 

Carbohydrates

Amylase and glucoamylase assist in the breakdown of starches, while alpha-galactosidase targets hard-to-digest carbs in beans and certain vegetables - so you can enjoy your favorite meals with less gas and bloating.

Fats

Lipase helps your body efficiently digest dietary fats. Research shows that lipase can ease feelings of fullness and discomfort after rich, high-fat meals.

Dairy sugars

Lactase breaks down lactose, the sugar in dairy products. Clinical studies suggest that lactase can significantly reduce digestive symptoms such as bloating and gas in those sensitive to dairy.

Plant fibers and complex polysaccharides

Cellulases help dismantle the tough cell wall components of plant foods that can otherwise ferment in the gut, causing gas and bloating.

Research suggests that:

  • Alpha-galactosidase: lowers gas production and gas-related symptoms after high-GOS (galacto-oligosaccharides) meals. May be helpful for IBS (Irritable Bowel Syndrome) symptoms when taken with high-GOS foods. PMID:28809383 
  • Lactase: reduces lactose-related symptoms in those with lactose intolerance. PMC7812489
  • Lipase: reduces post-meal fullness/bloating caused by high-fat foods. PMC4477989

Note for those with celiac disease: Enzymes with DPP-IV activity can help break down certain gluten fragments. However research clearly shows they do not prevent gluten-related immune reactions in celiac disease. This product is not intended for people who need to avoid gluten.

Supplement Facts
Serving Size: 1 Chewable Tablet
Servings Per Container: 90 servings per container
Amount Per Serving Daily Value
Enzyme Blend 250 mg
((DPP-IV Blend [Protease I, Protease II, Protease III, Protease IV & Protease V], Amylase, Lipase, Lactase, Hemicellulase, Beta Glucanase, Xylanase, Pectinase, Cellulase, Mannanase, Alpha-Galactsosidase, Glucoamylase))
*%
Manufactured: March 2025

Methyl-Life® supplements typically retain their potency for 2-3 years.  They should be stored in their original, tightly sealed containers in a cool, dry place away from heat, moisture, and direct sunlight.

Other Ingredients

Xylitol (Xylisorb®), microcrystalline cellulose (Microcel®), stearic acid, silicon dioxide, natural mint flavoring, sodium stearyl fumarate (PRUV®), monk fruit. Not a significant source of sugars.

Allergen & Safety Information

  • Does not contain: wheat, gluten, soy, dairy, tree nuts, animal products, or GMOs
  • No artificial ingredients or colorings
  • Sweetened with xylitol — do not give to pets

Suggested Use

General use: Take 1-2 chewable tablets after meals or as recommended by your healthcare professional.

  • Start with 1 tablet after a typical meal.
  • If you still feel heavy/full or anticipate a bigger/more challenging meal, consider 2 tablets.
  • For lactose-containing meals, ensure a serving that includes lactase is taken with or immediately after the dairy portion. PMC7318541
  • For high-fat meals, ensure a serving that includes lipase is taken with or immediately after the meal. PMC4477989

Professional guidance: If you have a diagnosed digestive condition (e.g., celiac disease, IBD), consult your clinician. This product does not replace medically necessary diets or therapies.

How much should you take?

Every person’s digestive needs vary depending on their diet, health status and natural enzyme levels .
For most people, 1 chewable tablet after meals provides effective daily support.
If you still experience occasional bloating, gas, or heaviness after large or more complex meals you may take 2 tablets.

What Research Shows

Clinical trials show that supplementary enzymes including lactase, alpha-galactosidase and lipase consistently benefit healthy digestion when taken with or immediately after food.

  • Lactase: Supports dairy digestion and reduces gas in people with lactose intolerance (PMC7812489)
    Alpha-galactosidase (α-GAL): reduces intestinal gas and bloating from legume-rich meals (PMC3849317)
  • Lipase: reduces postprandial fullness and bloating after high-fat meals in controlled human studies (PMC4477989)

Timing and Administration

For best results:

  • Take with or immediately after meals: enzymes must combine with food to be effective.
  • Chew thoroughly. Enzymatic action begins in the oral and gastric phases of digestion.
  • The natural mint flavor is pleasant to take after eating and helps freshen breath.
  • Take daily with meals that typically cause digestive discomfort (e.g., beans, dairy, high-fat foods).

Meal Size & Composition Tips

  • High in dairy: Take at least one tablet: lactase helps to break down milk sugar.
  • High in fat: Lipase supports fat digestion and may help reduce post-meal heaviness (PMC4477989).
  • Beans or cruciferous vegetables: alpha-galactosidase helps break down GOS sugars, reducing gas (PMID: 17151807).
  • High-protein or mixed meals: multi-protease system supports protein digestion, including partial breakdown of gluten-derived peptides via DPP-IV activity* (PMC11394543).

*Not intended to enable gluten consumption in individuals with celiac disease.

Professional guidance

If you have a diagnosed condition such as celiac disease, pancreatic insufficiency, or inflammatory bowel disease (IBD), consult your healthcare provider before supplementing with digestive enzymes.

  • Celiac disease: dipeptidyl peptidase IV (DPP-IV) enzymes  cannot fully detoxify immunogenic gluten peptides (PMC2708912).
  •  Pancreatic insufficiency: Lipase-only or OTC enzyme blends are not substitutes for prescription-strength pancrelipase (Pancrelipase Therapy).

Additional considerations

  • Can be taken daily or as needed.
  • Store in a cool, dry place.
  • Contains xylitol: do not feed to pets.
  • Not intended to replace medical treatment or physician-prescribed dietary restrictions.

Why Chewable Digestive Enzymes Matter

Proteins, starches and sugars, fats, dairy sugars and fibers each require specific enzymes for digestion. When enzyme production is insufficient, digestion may be sluggish or impaired. This can lead to symptoms such as bloating, excess gas and post-meal discomfort.

Supplementing with digestive enzymes supports the breakdown of macronutrients into beneficial vitamins, minerals and amino acids. Foods high in fiber, lactose and certain fats can be easier to digest and more nutritious when supported by digestive enzymes. Clinical trials show the enzymes alpha-galactosidase, lactase and lipase can reduce acute digestive symptoms when taken alongside a ‘trigger’ meal (PMC4923703).

Note: Enzymes with DPP-IV activity can partially break down proline-rich peptides (e.g., from gliadin), but they do not prevent immune system activation in celiac disease. AN-PEP (a specialized endo-prolyl protease) is shown to degrade gluten in the stomach and duodenum but this does not permit gluten consumption when medically contraindicated. A strict gluten-free diet remains the standard of care.

Key Scientific Findings

  • Alpha-galactosidase: Randomized trials show alpha-galactosidase reduces gas-related symptoms after meals containing high-fiber foods. Benefits are most appreciated when taken with high-GOS meals, including in individuals with IBS (PMID:17151807). PubMed+1
  • Lactase: Orally administered lactase taken with dairy reduces symptoms of lactose intolerance in adults, with efficacy depending on dose and formulation (PMC7812489).
  • Lipase: Acid-resistant lipase taken with high-fat meals may reduce postprandial fullness and bloating; similar effects observed with pancreatic blends after very high-fat foods (note: not a substitute for prescription Pancreatic Enzyme Replacement Therapy (PERT)). (PMC4477989) 
  • Gluten peptide handling (mechanistic context): AN-PEP (Aspergillus niger prolyl endoprotease) accelerates gastric and duodenal gluten degradation in human sampling studies. However,  reviews emphasize that most commercial  “glutenase” supplements don’t adequately neutralize immunotoxic epitopes sufficiently for celiac safety. A strict gluten-free diet remains essential for celiac disease. (PMC5032996)
  • Pediatric tolerance (alpha-galactosidase): Clinical data indicate good tolerability and symptom reduction in children with gas-related discomfort. (PMC3849317)  

Clinical Relevance

For people who experience post-meal discomfort related to specific foods, targeted digestive enzymes taken with or immediately after the offending foods can make a noticeable difference.

  • Beans/legumes or cruciferous vegetables → add alpha-galactosidase at the meal. Supplementation at the meal has been shown to reduce intestinal gas production and lower symptom scores in the hours following consumption.(PMID:17151807)
  • Dairy-containing meals → add lactase with the dairy portion. Co-administration with dairy significantly decreases digestive symptoms compared to placebo.(PMC7812489)
  • High-fat meals → add lipase at mealtime. Taken at mealtime, lipase reduces sensations of postprandial fullness and bloating. (PMID:25287168) PubMed
HOW WE HAVE HELPED OUR CUSTOMERS

Heidi D.

05/26/2025
Made a noticeable difference

Much to my delight, these chewable digestive enzymes made a noticeable difference in stomach bloating. I didn't realize how bad it really was until I bought these and saw the huge improvement in my what I thought was granny gut. If you know, you know:) Anyway, instead of resigning yourself to thinking granny gut might be due to menopausal hormone shifts/fluctuations, give these a try and see if you notice a difference. I certainly did.

HOW WE HAVE HELPED OUR CUSTOMERS

Wanda P.

Verified Buyer
07/04/2025
Real Experience

I chew one or two depending on what I ate or how heavy the meal and these Digestive Enzymes seem to immediately ease my tummy, I don't feel as bloated and they help with acid reflux too. They taste very good, not overwhelmingly minty or chalky, Highly recommend.

HOW WE HAVE HELPED OUR CUSTOMERS

Mary

Verified Buyer
11/04/2025
Real Experience

I have tried many Dig. Enz. supplements. They all left me with more problems rather than solving any problems. This supplement has been a welcome surprise. It dissolves on the tongue with a minty flavor. It has pleasantly addressed issues with garlic and onion in the FODMAP category. I can happily eat pizza and spaghetti dishes again without bloat and next morning worries. I bought another bottle during the anniversary sale I am so confident of its efficacy. Thanks. Methyl-Life®. You've done it again.

HOW WE HAVE HELPED OUR CUSTOMERS

Linda B.

Verified Buyer
10/06/2025
Real Experience

I think these are helpful. I don't seem to have as much excess mucus after eating dairy.
Chewable Digestive Enzymes
$46

Traceable Ingredients You Can Trust

Every ingredient is sourced for purity, backed by clinical evidence, and rigorously tested for safety and bioavailability. Because in supplements, not all ingredients are created equal — and your body deserves only the most effective forms.

Supports protein digestion & gluten peptide breakdown

Protease Complex (I-V) with DPP-IV Activity

Proteases catalyze the hydrolysis of dietary proteins into amino acids and peptides, assisting in the efficient utilization of protein-based foods.
This formula’s inclusion of DPP-IV (dipeptidyl peptidase-IV) is designed to help degrade proline-rich gluten peptides that are otherwise resistant to digestion.

Clinical data suggest proteolytic enzyme blends containing DPP-IV may improve postprandial tolerance and reduce  protein-related digestive discomforts in non-celiac individuals (PMC10814021), (PMC6143542).

LEARN MORE: Did You Know?

Unlike many single-enzyme supplements, DPP-IV is active in the small intestine, where gluten and casein fragments are most problematic.
However, DPP-IV does not fully neutralize  gluten peptides sufficiently for individuals with celiac disease - meaning enzyme support is adjunctive, not a replacement for a gluten-free diet (PMC8541236).

Target complex starches & carbohydrates

Amylase & Glucoamylase

Amylase begins starch digestion by breaking long-chain polysaccharides into maltose and dextrins, while glucoamylase completes the process by converting them into glucose for absorption.

This dual-enzyme system helps minimize starch-related bloating or fermentation, improving carbohydrate tolerance.

LEARN MORE: Did You Know?

Human studies demonstrate that dietary amylase supplementation supports more efficient postprandial carbohydrate breakdown and reduces undigested residues that can otherwise lead to fermentation and gas production (PMID:2423408).

Supports fat digestion & reduces post-meal fullness

Lipase

Lipase assists in breaking down triglycerides into fatty acids and glycerol, supporting fat absorption and uptake of key fat-soluble vitamins (A, D, E, K).
Clinical research shows that acid-stable lipase reduces bloating, heaviness and fullness following high-fat meals (PMC4477989).

LEARN MORE: Did You Know?

Unlike pancreatic enzymes, which act primarily in the intestine, acid-resistant lipase functions in the stomach’s acidic environment, beginning fat digestion early - a critical advantage for rapid symptom relief in mixed or high-fat meals (PMC3996833).

Supports dairy digestion & lactose tolerance

Lactase

Lactase breaks down lactose, the natural  sugar found in milk and dairy products. When taken with dairy products, lactase reduces symptoms of lactose intolerance and lowers hydrogen breath test values - the gold-standard measure of lactose malabsorption. (PMC4481453)

LEARN MORE: Did You Know?

Lactase works best when ingested with the first bite or sip of dairy. Clinical studies show that timing and enzyme dose are directly related to efficacy - taking lactase before or long after a meal may diminish benefits (PMC7812489).

Reduces gas and bloating from beans & cruciferous vegetables

Alpha-Galactosidase

Alpha-galactosidase breaks down galacto-oligosaccharides (GOS) - carbohydrates found in legumes and certain vegetables that are known to cause significant gas and bloating. Supplementation significantly reduces intestinal gas and bloating following GOS-rich meals (PMID:17151807).

LEARN MORE: Did You Know?

By breaking down GOS in the upper small intestine, alpha-galactosidase prevents undigested carbohydrates from fermenting in the colon. Randomized controlled studies confirm a measurable reduction in breath hydrogen and symptom scores (PMID:17151807).

Support fiber digestion & plant nutrient release

Cellulase, Hemicellulase, Beta-Glucanase, Xylanase, Mannanase & Pectinase

These plant-cell-wall enzymes help break down dietary fibers and complex polysaccharides that are resistant to human digestion.
Their combined action reduces intestinal gas, promotes smoother digestion of plant-based meals and supports micronutrient release from fibrous foods (PMC7074226).

LEARN MORE: Did You Know?

By degrading cellulose and hemicellulose bonds, these enzymes help liberate bound phytonutrients and B-vitamins from plant material - enhancing their availability for absorption (PMC9785684).

Support gut comfort & tissue balance

Natural Enzyme Cofactors - Bromelain, Papain & Serrapeptase

Bromelain (pineapple enzyme), Papain (papaya enzyme) and Serrapeptase are natural proteolytic enzymes studied for their anti-inflammatory and mucolytic properties. They complement digestive enzymes by supporting tissue repair, gastric comfort and healthy inflammatory response.

LEARN MORE: Did You Know?

  • Bromelain has demonstrated anti-inflammatory and gastroprotective activity in clinical and preclinical studies (PMC4998156).
  • Papain aids in protein digestion and supports healthy mucosal balance (PMC11727233).
  • Serrapeptase contributes to systemic enzyme therapy research for supporting natural recovery processes (PMC7585045).

Methyl-Life® Chewable Digestive Enzymes contains no unnecessary excipients, synthetic colors, artificial preservatives, or common allergens. It is 100% free from gluten, soy, dairy, GMOs, animal-derived ingredients, and the EU’s top 14 allergens.

Every batch is third-party tested for purity, potency, and safety, manufactured in NSF-certified, cGMP-compliant facilities, and rigorously evaluated to ensure you’re getting clean, clinical-grade nutrients — nothing more, nothing less.

EU’s top 14 allergens

  • Cereals containing gluten - wheat (such as spelt and khorasan wheat), rye, barley, oats. Note: The cereal name, e.g., 'wheat', must be declared and highlighted, not 'gluten'.
  • Crustaceans, e.g., crabs, prawns, lobsters
  • Eggs
  • Fish
  • Peanuts
  • Soybeans
  • Milk
  • Nuts (almonds, hazelnuts, walnuts, cashews, pecan nuts, brazil nuts, pistachio nuts, macadamia/Queensland nut). Note: The name of the nut, e.g., 'almond', must be declared and highlighted, not 'nuts'.
  • Celery
  • Mustard
  • Sesame seeds
  • Sulphur dioxide and sulphites (at concentrations of more than 10 mg/kg or 10 mg/L in terms of total sulphur dioxide) – used as a preservative
  • Lupin 
  • Molluscs, e.g., mussels, oysters, squid, snails
Broad-Spectrum Enzymes for Optimal Digestion Relief

Clinically Researched Digestive Comfort

This clean, mint-flavored chewable is designed to support healthy digestion of: proteins, carbohydrates, fats, dairy sugars and plant fibers.

This clinically researched formula helps to relieve feelings of fullness, gas and bloating while facilitating the breakdown of beneficial nutrients. Evidence in humans shows specific enzymes (alpha-galactosidase, lactase, lipase) reduce acute post-meal symptoms when timed with the trigger meal.

Targets Multiple Food Triggers

Beans/legumes and certain veggies: Alpha-galactosidase helps break down galacto-oligosaccharides (GOS), which commonly cause gas and bloating. Studies suggest that supplementing with alpha-galactosidase reduces gas-related symptoms when taken with meals containing GOS. (PMC10577458)

Dairy (lactose): Lactase taken with dairy reduces GI symptoms in lactose-intolerant adults in controlled trials. (PMC7812489) 

High-fat meals: Lipase may help to reduce fullness and bloating after high-fat meals. This is not a substitute for prescription PERT (Pancreatic Enzyme Replacement Therapy). (PMC4477989)

Proteins (Including Proline-Rich Peptides): A multi-protease formula including Dipeptidyl Peptidase-4 (DPP-IV) supports protein metabolism. Note: DPP-IV alone is not a treatment for celiac disease. (PMC7400306) 

Research Insights: 

  • Alpha-galactosidase: RCTs demonstrate reduced gas and bloating after consumption of legumes and other foods high in GOS. (PMID:17151807)
  • Lactase: Double-blind trials confirm symptom improvements when taken with lactose. (PMC7812489)
  • Lipase: Crossover human data show reduced fullness/bloating after high-fat meals vs. placebo. (PMC4477989)

Works Where Food Is: Gastric & Luminal Phases

Unlike long-latency supplements, digestive enzymes act where food is present.  Research demonstrating symptom relief consistently uses  dosing with or immediately after the meal, ensuring enzyme-substrate contact during digestion. Lipase studies specifically used gastric-resistant formats to survive acidity). (PMC4477989)

Research Highlights: 

  • Lipase timing & format: Acid-resistant lipase given with high-fat loads shows timing-dependent reductions in fullness and bloating. (PMC4477989)
  • Hydrogen breath outcomes: Many enzyme trials use breath hydrogen as an objective measure of carbohydrate malabsorption; improvements correlate with reduced symptoms. (PMC8002624)

Enhances Food Breakdown for Better Nutrient Liberation

Digestive enzymes break foods down into absorbable units (amino acids, simple sugars, fatty acids). When natural enzyme production is inefficient, supplementation can optimize the metabolism of vitamins and minerals bound within plant matrices while reducing fermentable residue linked to gas and bloating.

Research suggests that pairing digestive enzymes with meals high in GOS, lactose and/or fat can relieve or prevent digestive discomfort during the same meal. (PMC10459152)

Scientific Support Summary

  • GOS digestion → less gas: Alpha-galactosidase lowers breath hydrogen and gas scores after legume meals (randomized, double-blind). (PMID:17151807)
  • Lactose digestion → fewer symptoms: Oral lactase reduces hydrogen breath and GI symptoms in lactose intolerance when ingested with dairy. (PMC7812489)
  • Fat digestion → less fullness: Acid-resistant lipase reduces postprandial fullness/bloating in controlled human studies. (PMC4477989)

Designed for Common Food Sensitivities

Many people  experience food-triggered discomfort (beans/legumes, dairy, high-fat meals). This formula combines  alpha-galactosidase, lactase, lipase, amylase/glucoamylase, proteases (including  DPP-IV) and plant-cell-wall enzymes (cellulase/hemicellulase/xylanase/pectinase/beta-glucanase/mannanase) to reflect the complexity of mixed meals.

Scientific Foundation

  • Celiac Disease Caveat: Reviews emphasize  that available DPP-IV/ASP supplements do not reliably detoxify immunogenic gluten epitopes; a strict gluten-free diet remains essential for celiac disease. Enzyme support is adjunctive digestive aid, not a therapy for Celiac Disease. (PMC7400306)
  • High-fat symptom relief: Lipase-focused or pancreatic blends studies show to reduce post-meal fullness and bloating in controlled settings. Effects are acute and meal-linked. (PMC4477989)  

Frequently Asked Question

How should I take this? Timing matters?
Take 1-2 chewable tablets with or immediately after meals for optimal digestive support
Can this help with lactose intolerance symptoms?
Yes, studies show that taking lactase with dairy can reduce digestive symptoms in people with lactose intolerance. The level of benefit can vary depending on the dose, the enzyme formulation and how sensitive you are to lactose.
What about gluten? Does the DPP-IV activity mean I can eat gluten?
No. DPP-IV helps break down certain proline-rich peptides, but research shows that typical “glutenase” supplements cannot metabolize, neutralize gluten or prevent immune activation in celiac disease. Patients with celiac disease must maintain a strict gluten-free diet.
How quickly might I notice the effects?
Most people report significant relief from their usual symptoms when taking Chewable Digestive Enzymes with meals containing lactose, beans/legumes, or high amounts of fat. Long-term management of IBS symptoms varies between individuals and depends significantly on personal diet.
Any safety considerations?
Clinical trials indicate that digestive enzyme supplements including are alpha-galactosidase and lactase are generally well-tolerated. If you have celiac disease, IBD, significant GI (gastrointestinal) disease, are pregnant/nursing or have food allergies, consult your clinician.
Storage & daily use
Use daily as needed with meals. Store in a cool, dry place with the lid closed.
Will this help with gas after beans/legumes or certain vegetables?
Often, yes. Alpha-galactosidase specifically targets gas-forming galacto-oligosaccharides (GOS) present in beans, legumes and some vegetables. Studies show that this enzyme helps to reduce breath gas-related symptoms after high-GOS meals, including in those with IBS.
Does it reduce heaviness after high-fat meals?
Yes, research has shown that supplementary lipase may reduce fullness and bloating after a high-fat meal. Pancreatic enzyme blends have similarly reduced post-prandial symptoms after very high-fat foods. (Note: This product is not a prescription pancreatic enzyme replacement.)
Is it useful for IBS?
IBS symptoms can vary significantly between individuals, particularly when it comes to ‘trigger’ foods. For people sensitive to Galacto-oligosaccharides (GOS), taking alpha-galactosidase alongside high-GOS foods may help to reduce symptoms.
Does this replace prescription enzymes (e.g., for pancreatic insufficiency)?
No. This is a dietary supplement designed to be taken with balanced meals. It is not intended to replace prescription pancreatic enzyme therapy. Consult your clinician about any prescription needs.
Can I take this with probiotics or PPIs (Proton Pump Inhibitors)?
There’s no known contraindication between standard digestive enzyme supplements, probiotics and acid-reducing medications. However, individual responses can vary and enzyme activity can be pH-dependent. If you are taking PPIs, check with your clinician.

Clinically Studied, Backed by Real Science

Digestive enzyme supplementation has been investigated in human trials and meta-analyses for its role in improving meal-related discomfort (bloating, gas, fullness), enhancing macronutrient breakdown and supporting nutrient absorption.When timed with food and matched to specific substrates, multi-enzyme formulations consistently demonstrate measurable digestive benefits.

Supports Healthy Digestion and Post-Meal Comfort

Clinically shown to relieve bloating, distension and digestive heaviness

Broad-spectrum digestive enzyme therapy has been repeatedly shown in human studies to improve digestion, reduce gas production and relieve abdominal discomfort after meals. By breaking down proteins, fats and complex carbohydrates more efficiently, enzyme blends help normalize post-meal transit time and nutrient absorption (PMC4923703).

In a randomized, double-blind, placebo-controlled crossover study, a multi-enzyme supplement taken with a standardized test meal led to a 68 % reduction in abdominal distension at 90 minutes and a marked decrease in bloating intensity compared with placebo. No adverse effects were reported (PMID:33619835).

Evidence-Based Insight: Clinical enzyme therapy acts quickly - most measurable relief occurs within 30-90 minutes of ingestion, demonstrating that the enzymes function locally in the gut to hydrolyze food components before fermentation can occur (PMC11727233).

Highlighted Study:
A controlled human trial found that a multi-enzyme formulation containing amylase, protease, lipase and cellulase significantly reduced post-meal bloating and fullness compared with placebo (PMC6249666).

Read the Study - PMC6249666

NEW Chewable Digestive Enzymes

Real-world relief for bloating, gas and sluggish digestion - explained by Jamie from Methyl-Life®

In this short, easy-to-understand video, Jamie from Methyl-Life® explains how the new Chewable Digestive Enzymes help your body naturally handle everyday meals - from dairy and gluten to protein, fats and starches. She covers why some foods trigger discomfort, what happens when enzyme levels drop with age or stress and how targeted enzyme support can make meals feel lighter and more comfortable.

This formula was designed for real life - whether you’re eating at home, dining out or experimenting with new foods - offering quick digestive relief in a natural-tasting mint chewable.

Recap: What You’ll Learn in This Video

  • Why modern diets and stress can lower your body’s enzyme supply
  • How multi-enzyme support helps break down complex foods
  • Why gluten and dairy are harder to digest - and how DPP-IV helps
  • The role of chewable delivery for fast, effective digestion
  • How Methyl-Life®’s formula stands out for purity, safety and convenience

Why Digestive Enzymes Matter

Your digestive system depends on enzymes to unlock nutrients from food. But modern diets, processed foods and aging can lower enzyme production, leading to bloating, gas and sluggish digestion. Supplementing with a broad-spectrum enzyme blend helps restore balance by pre-digesting food before it reaches the intestines - reducing fermentation, heaviness and discomfort after eating.

Clinical trials show that enzyme supplementation can reduce post-meal distension by 58-68 % within 90 minutes (PMC4923703).

What Makes This Formula Different

This chewable blend contains protease, lipase, amylase, lactase, alpha-galactosidase and DPP-IV - covering every major macronutrient category.

  • DPP-IV supports digestion of gluten and casein (milk proteins) for those with mild sensitivities.
  • Lactase helps the body process dairy sugars and reduce bloating.
  • Lipase and amylase improve fat and carbohydrate breakdown, enhancing nutrient absorption.
  • Cellulase and hemicellulase help ease gas caused by fibrous vegetables and plant matter.

Together, these enzymes mimic the body’s natural digestive process - helping you feel lighter and more comfortable after meals.

Evidence-Based Insight

Peer-reviewed studies demonstrate that taking multi-enzyme blends before or with a meal can:

  • Significantly reduce post-prandial bloating and gas (PMC6249666)
  • Improve nutrient bioavailability, including amino acids and fat-soluble vitamins (PMC7393990). 
  • Enhance comfort and digestion in individuals with functional dyspepsia and mild sensitivities (PMC11960677). 

Why It’s Chewable - and Why That Matters

Unlike capsules, the chewable format starts working as soon as you begin chewing - activating amylase and glucoamylase in the mouth. This early phase of digestion sets up the rest of the enzymatic process downstream, so your stomach and intestines don’t have to “catch up.”
Plus, the mild mint flavor makes it enjoyable and portable - perfect for restaurants, travel or anyone who dislikes swallowing pills.

Why Jamie Created It

After years of researching gut and methylation health, Jamie designed this formula for people who experience recurring discomfort after meals but want a clean, non-pharmaceutical solution that’s safe for daily use. Her goal was to create a supplement that not only helps the gut digest food more efficiently, but also supports overall nutrient utilization and systemic well-being.

Related Articles

Popular reads from our experts

Methyl-Life® Chewable Digestive Enzymes - Complete Enzyme Support for Gut Comfort, Nutrient Absorption & Post-Meal Relief

Methyl-Life® Chewable Digestive Enzymes deliver broad-spectrum digestive support in a convenient, mint-flavored chewable designed to ease bloating, fullness and sluggish digestion after meals. This multi-enzyme formula combines protease, amylase, lipase, lactase, cellulase, alpha-galactosidase and DPP-IV to break down proteins, fats, carbohydrates, fiber, gluten and dairy - restoring digestive efficiency from the very first bite of food.

Formulated for individuals who experience post-meal discomfort, digestive sensitivity or nutrient malabsorption, this professional-grade supplement supports a balanced gut environment and smoother digestive function without the use of harsh chemicals or pharmaceuticals.

Understanding Digestive Enzyme Deficiency and Modern Digestion Challenges

Digestive discomfort - including bloating, distension and sluggishness after eating - often stems from enzyme insufficiency, a condition where the body doesn’t produce enough digestive enzymes to fully break down food. This can occur naturally with age, stress, poor diet or use of certain medications like proton pump inhibitors (PPIs). When food isn’t completely digested, it ferments in the gut, producing gas, pressure and discomfort while limiting nutrient absorption