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L-Methylfolate Methylated Vitamins MTHFR Supplements Methyl B12 B12 SupplementsPopular Picks
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The Methyl-Life® B12 Supplements support methylation, energy, and overall wellness with active forms of vitamin B12 and folate. Key nutrients like Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin, and L-Methylfolate promote red blood cell formation, homocysteine metabolism, and cognitive clarity. Formulated for absorption and purity, these supplements help maintain vitality and balance. Consult a healthcare provider before use.
Bioavailable B12 for daily energy and nervous system health
Foundational B12 and Folate Support
This category includes well-tolerated, active B12 forms in sublingual tablets designed for maximum absorption and easy use. Ideal for maintaining healthy red blood cells, nervous system function, and cellular energy on a daily basis.
- Supports Healthy Red Blood Cells & Myelin
- Promotes Healthy Brain Function & Detoxification
- 3rd-Party Tested for Purity, Potency & Safety
- All 3 Bioactive Forms of B12 for Full-Spectrum Absorption
- Methylcobalamin B12, Hydroxy B12 & Adenosylcobalamin
- 3rd-Party Tested for Purity, Potency & Safety
Therapeutic blends supporting methylation and metabolic function
Methylated B12 & Folate Combinations
Formulations combining methylated B12 and potent doses of L-Methylfolate to enhance neurotransmitter synthesis, energy metabolism, and cardiovascular health. Suitable for individuals requiring targeted methylation support, including those with MTHFR gene variants.
- Bioactive L-Methylfolate 3 Mg & Methylated B12
- Great for Bypassing MTHFR Mutations
- 3rd-Party Tested for Purity, Potency & Safety
- Therapeutic, Professional Strength L Methylfolate
- Bioactive, Sublingual Vitamin B12 Tablets
- 3rd-Party Tested for Purity, Potency & Safety
- Bioactive L Methylfolate 15 Mg with Mood-Boosting Power2
- Vitamin B12 with Methyl for Neurotransmitter Synthesis10
- 3rd-Party Tested for Purity, Potency & Safety
Methyl-Life® B12 Supplements: Active Support for Methylation, Energy, and Wellness
Why B12 and Folate Matter
Vitamin B12 and folate work together in the methylation cycle, a vital process for homocysteine metabolism, neurotransmitter production, and DNA synthesis.* Active forms like L-Methylfolate and methylcobalamin can be directly utilized by the body, making them more efficient for those seeking reliable nutrient support.
Foundational B12 & Folate Support
Gentle Daily Options for Energy and Nervous System Health
These foundational supplements feature active, well-tolerated B12 forms in convenient sublingual delivery, supporting red blood cells, nervous system function, and energy production on a daily basis.*
- Hydroxy B12 Sublingual Tablets – Gentle, bioavailable support for brain and detox pathways.
- Methylcobalamin B12 Complete 5000 mcg – All 3 bioactive forms of B12 (methyl, hydroxy, adenosyl) for full-spectrum absorption.*
Methylated B12 & Folate Combinations
Intermediate Formulas for Targeted Methylation Support
Formulas combining methylated B12 with L-Methylfolate promote neurotransmitter balance, methylation efficiency, cardiovascular wellness, and overall vitality
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Customer Support Hours (PST)
Monday-Friday (8:00 am - 7:00 pm)
support@methyl-life.com
Phone: (571) 308-2172
Methylation & Nutritional support for MTHFR since 2011.
Every batch is third-party tested for purity, potency, and safety, manufactured in NSF-certified, cGMP-compliant facilities, and rigorously evaluated to ensure you’re getting clean, clinical-grade nutrients — nothing more, nothing less.
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Let customers speak for us
from 1228 reviewsThese digestive enzymes work really well and have noticeably improved my digestion and food sensitivities. I experience much less bloating and discomfort after meals. They’re chewable and very effective, but strong, so it’s important to chew them as directed. When used correctly, they’re an excellent product and I will definitely repurchase.
Customized methylation... I love this product!
Great tasting easy to take.
Works well for my son and I.
Works for me
I have noticed an increase in energy in myself and my children, once we started taking this daily at the mg our provider recommended.
For a year, I tried a well known B12 from another company at a much higher dose, but I felt it was not helping. I have Fibromyalgia and Dysautonomia so it was suggested to me to try the Hydroxy form of B12 so as not to over stimulate my nervous system anymore than it already was, and to start at a very low dose. I like this company, the quality of their products, the information they freely share with their customer base and their customer service. I know this is the correct form of B12 for me as I actually feel better, a bit more energy even at such a low dose. Thank you.
I used a much higher dose by a different name brand, a well known one, but after a year of use, I felt no different so I did some research trying to find a different B12 and folate to try. I have just started using this one, but I like the quality of the product, I like that it is a chewable so easier absorption, and I Love all the free information available on the website.
I did order this supplement before and I intend to continue to buy.
The vitamins are fine, just really expensive,
I have used the product for years, recommend by my doctors
Good transaction
Great product. Does not give any stomach discomfort. I have a lot more energy using this product.
Great! I have a MTHFR gene defect.
It’s the best
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