Chewable Methylated Multivitamin - L-Methylfolate + Active B12 - MTHFR/Pregnancy/Children

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A delicious chewable Methylated Multivitamin with Cognitive & Energy promoting nutrients to support MTHFR and other genetic challenges

Methyl-Life’s® Methylated Multivitamin has a NEW FLAVOR! It's a delicious Sweet 'n Tart Cherry Berry flavored chewable that tastes even better than before (your kids will love it). It holds many of the needed ingredients for methylation to occur optimally in the body. It’s been specially formulated with L-Methylfolate and Active B12 to:
    • Promote glutathione, your body’s strongest antioxidant
    • Boost serotonin, an important neurotransmitter
    • Reduce harmful homocysteine levels in the body
    • Support fertility, pregnancy and fetal health
    • Help repair the myelin sheath for nerve health
    • Support RNA/DNA build blocks
    • Support your thyroid and liver
This formula is BOASTING the PUREST proven L-Methylfolate on the planet, Magnafolate® PRO. This form of L-Methylfolate, is more identical to the pharmaceutical version of methylfolate, AND it tested 3 times more pure in a recent study. Our formula is Gluten, Dairy and Soy free. This multivitamin also contains:
    • The energy-supporting B vitamins along with their co-factors supporting the thyroid
    • Patented Sucrosome® minerals
    • Vitamins A, D3, E and bioactive K2
    • A new ATP energy formula (Panmol® NADH + MicroActive® CoQ10)
    • TMG is built in for lowering homocysteine levels in the body
    • A specialized, soy-free form of choline that crosses the blood brain barrier (Citicoline) for improved cognitive health
    • And another brain health nutrient, soy-free Phosphatidylserine which contains essential phospholipids supporting healthy cognition
    • Artichoke extract and Milk Thistle to support the liver
The Methylated Multi may reduce homocysteine levels in the body. It can be taken along with other Methyl-Life® products that have methylfolate in them (if one wishes to intake higher methylfolate doses). Methyl-Life’s® Methylated Multivitamin is one of the best formulas you’ll find out in the market today. You may find this multi can also act as a nice prenatal without iron or Vitamin C, as well as a great kid’s multi-vitamin (though you’ll want to consider adjusting the number of tablets given as a serving if you take it for these other purposes).

WARNING – How much is right for you to take?

Talk to your doctor about what’s best for you. Check out our dosage information to learn more about what some doctors recommend.

SUGGESTED USE:  Chew 1-4 tablet(s) daily with food (for best absorption), or as directed by your health care professional.
Great for teeth, NOT FOR ANIMALS (contains xylitol).

Serving Size: 4 Chewable Tablets
30 servings per container Amount per Serving % Daily Value

Vitamin A (as Retinyl Palmitate - 2,000 IU)

600 mcg RAE 67%
Vitamin D (as Cholecalciferol [Vitamin D3])
33 mcg (1,333 IU) 165%
Vitamin E (as d-a-Tocopheryl Acid Succinate[Novatol™])
8 mg (121 IU) 53%
Thiamin (Vitamin B1)(as Thiamin HCI) 2 mg 167%
Riboflavin (Vitamin B2)(as Riboflavin 5 Sodium Phosphate) 13 mg 1,000%
Niacin  13 mg NE 81%
Vitamin B6 (as Pyridoxal 5 Phosphate) 3 mg 176%
Folate (as L-5-Methyltetrahydrofolate, Calcium [equal to 1,000 mcg of Magnafolate® PRO]) 1,324 mcg DFE 331%
Vitamin B12 (as Hydroxocobalamin Acetate) 333 mcg 13,875%
Biotin  120 mcg 400%
Pantothenic Acid (as D-Calcium-Pantothenate) 40 mg 800%
Iodine (as Potassium Iodide) 67 mcg 45%
Zinc (as Sucrosomial Zinc Oxide (UltraZin®)) 10 mg 91%
Selenium (as Sucrosomial Sodium Selenite (UltraSel®)) 67 mcg 122%
Manganese (Manganese Bisglycinate Citrate (ALBION)) 2 mg 87%
Chromium (Chromium Nicotinate Glycinate (ALBION)) 23 mcg 66%
Molybdenum (Molybdenum Glycinate(ALBION)) 13 mcg 29%
Artichoke (Leaf) Extract 5% Cynarin  33 mg **
Citicoline Sodium 98% 33 mg **
Coenzyme Q10 25% (MicroActive®) 33 mg **
Phosphatidylserine 20% (from Lecithin)
33 mg **
Milk Thistle (Seed) Extract 80% Silymarin
33 mg **
Trimethylglycine (TMG) 33 mg **
Para-Amino Benzoic Acid (PABA) 17 mg **
Benfotiamine (fat soluble Vitamin B1) 16 mg **
Reduced NADH Complex (9.5% NADH® PANMOL)(NADHMicro) 7 mg **
Vitamin K2 (as Menaquinone-7) 175 mcg **

** Daily Value not established

OTHER INGREDIENTS:  Inositol, Medium Chain Triglycerides, xylitol (Xylisorb®), natural flavors (dextrose, silicon dioxide, citric acid, propylene glycol, sugar, fruit & vege juice & concentrates, phosphoric acid, maltodextrin, potassium bitartrate, calcium lactate),  microcrystalline cellulose (Microcel®), malic acid, sodium stearyl fumarate (PRUV®), monk fruit extract.  Trivial source of calories.

PRODUCT CONTAINS NO: wheat, gluten, dairy, egg, soy, fish, shellfish, yeast, sodium, nuts, caffeine, artificial colorings, preservatives or flavorings, bisphenol-A (BPA), or phthalate.

What is the Chewable Methylated Multivitamin?

The Chewable Methylated Multivitamin is a comprehensive multivitamin formula containing L-Methylfolate and Active B12, specifically designed to support individuals with MTHFR mutations, pregnant women, and children.

What are the key features of the Chewable Methylated Multivitamin?

This multivitamin provides essential nutrients in a chewable form, making it convenient for individuals with MTHFR mutations, pregnant women, and children to meet their nutritional needs. With L-Methylfolate and Active B12, it offers optimal support for methylation and overall health during pregnancy and childhood.

What are the potential benefits of the Methylated Multi?

The Methylated Multi may help reduce homocysteine levels in the body, contributing to overall health and well-being. It can also be safely taken alongside other Methyl-Life® products containing methylfolate for those seeking higher doses of methylfolate.

 How can I get more information on MTHFR?

check out our Help for MTHFR Newbies page.

Why is Methyl-Life’s® Methylated Multivitamin considered one of the best formulas available?

Methyl-Life’s® Methylated Multivitamin stands out as an exceptional formula in the market today, offering comprehensive nutritional support with its methylated ingredients. It can serve as an excellent prenatal option without iron or Vitamin C and is also suitable as a high-quality multivitamin for children, although serving sizes may need adjustment for these specific purposes.

 What if my blood serum B12 level test comes back as high, does that mean I don’t need B12?

The most important thing to realize is that blood tests for B12 are highly inaccurate at detecting actual cellular levels of B12 (meaning the B12 that’s available for the cells to use). Studies have shown that people can have high or normal B12 levels in the blood and actually show virtually no B12 in the spinal fluid, meaning the B12 is not being transported from the blood stream into the cells where it should be absorbed and used.

How should I use this product?

The suggested use for this product is to chew 1-4 tablets daily with food for optimal absorption. It is recommended to follow the dosage instructions provided by your healthcare professional.

 What does sublingual mean and why isn’t your product labeled as “sublingual”?

It’s a well-known fact that B12 does not absorb well through the gut, so taking B12 via sublingual or mouth absorption is best (holding it under the tongue or between the gums and cheek is most common). Consider some form of liquid or tablet/lozenge that can be sucked on or dissolved in the mouth. Holding the B12 in your mouth for at least 90 seconds is good and the longer you can leave it in your mouth, the better for sublingual absorption (as opposed to gut absorption).
Note: different manufacturers use different terms for tablets that are meant to dissolve sublingually in the mouth, but “sublingual” is considered a pharmaceutical term by the FDA, so dietary supplements are moving away from using that term. However, it doesn’t really matter what term you use (chewable tablet, lozenge, sublingual tablet, liquid, etc.) for maximum absorption the main idea is to hold it in your mouth for 90 seconds or more if you can (if you forget, don’t worry, since you’re taking the active form, your body will still get some benefit even if you swallow it whole).

Another way to absorb B12 is muscularly through shots, however, the research tells us that sublingual (or mouth) absorption is equally as effective as muscular absorption … and shots may cost significantly more money. Also, be aware with shots (many doctors still give cyanocobalamin shots) that though you may need higher doses of active B12s (like myself), you may not do well when given higher doses of cyanocobalamin in a shot because your body may not be able to do the conversions and you could have negative side effects.

 My doctor said that because I have MTHFR, I should be taking methylcobalamin as my B12 form, why are you suggesting these other forms too?

One of the most common other nutrients to consider when supplementing the methylation cycle is the proper form of B12. There are 3 different types of B12 that are considered very beneficial to the body (hydroxocobalamin, methylcobalamin or adenosylcobalamin). Many automatically think that if you have an MTHFR defect, then you need the form of B12 called methylcobalamin, but that is simply NOT true.

It’s important to realize that the MTHFR status does not necessarily determine the type of B12 that’s best for you, instead it’s the status of genes like COMT, MTR, MTRR as well as VDR Taq. It is true that methylfolate and methylcobalamin work together synergistically along the methylation cycle pathway, but that doesn’t necessarily mean that if you tolerate methylfolate well you’ll also need, want or tolerate methylcobalamin well (even if that’s what most doctors, nutritionists, etc. are currently saying right now).

It seems there may be a general lack of education available to most doctors about the different forms of B12 and what those forms are as well as how they get converted within the body and what each is most beneficial for (not to mention which set of genes or genetic mutations could benefit most from which B12 type). So do your homework when it comes to B12 to see which you may tolerate best.

The most common form of B12 that you’ll find everywhere is cyanocobalamin and it is not very active or beneficial to the body because the absorption rate is fairly low, that’s because the body has to convert it first into hydroxocobalamin, and from there the hydroxocobalamin has to be converted into both adenosylcobalamin and methylcobalamin. But if the body has genetic mutations then these conversions don’t happen well at all and the effect is the body does not get the absorption or use of the nutrient.

 I have my 23andme test results, how can I use those to know which form of B12 I might best tolerate?

If you have your 23andme genetic test results, you can use those to help guide you as you try the specific B12 forms to see how they do for you. You’ll notice below that, according to Dr. Amy Yasko, the most well tolerated active form of B12 for folks seems to be hydroxocobalamin. Every single one of the genetic combinations she lists below should be able to tolerate B12 in the form of hydroxocobalamin (and this is why our methylation protocol suggests hydroxocobalamin as the B12 form to begin with):

    • Folks with multiple COMT mutations tend to do very well with hydroxocobalamin (it helps mop up excess peroxynitrites which can cause problems)
    • Folks with MTR & MTRR mutations may do well with methylcobalamin & adenosylcobalamin supplementation
    • And Dr. Amy Yasko ( talks about folks with a particular mutation status for COMT & VDR Taq as best needing the below forms of B12:
COMT V158M VDR Taq B12 Types That Should Be Tolerated
– – + + (TT) All 3 types of B12
– – + – (Tt) All 3 types of B12 with less Methylcobalamin
– – – – (tt) Hydroxocobalamin and Adenosylcobalamin
+ – + + All 3 types of B12 with less Methylcobalamin
+ – + – Hydroxocobalamin and Adenosylcobalamin
+ – – – Hydroxocobalamin and Adenosylcobalamin
+ + + + Hydroxocobalamin and Adenosylcobalamin
+ + + – Hydroxocobalamin and Adenosylcobalamin
+ + – – Mostly Hydroxocobalamin

Please Note

Before making a purchase of any of our products, Methyl-Life® recommends consulting with a healthcare professional - especially if you have any questions. Methyl-Life® cannot assume responsibility for adverse reactions or perceived negative side effects resulting from the use of our products.

For customers who have not used Methyl-Life® products before, we recommend starting with a single bottle before considering larger orders. Additionally, we encourage you to review our dosage and methylation protocol pages and consider beginning with a lower dose product to ensure a smooth integration with the ingredients before progressing to higher dose options.

Methyl-Life® generally does not accept returns for large orders. If you choose to return three unopened bottles from a 4-pack purchase, you will receive a full refund, excluding the cost of one bottle charged at full price.


Within 45 days of your order within the United States, you can return any unopened item shipped to you by Methyl-Life® as long as all seals are intact. To initiate a return, please email us using the Contact Us form, providing your order details and tracking information for the return product shipment sent to:  P.O. Box 33606, Seattle, WA 98133. Please note that return shipping costs are the responsibility of the customer, and we recommend considering insurance for the return package. Refunds will be processed within 10 business days of receiving the returned item, and you will receive an email confirmation once the refund is complete. Please be aware that depending on your financial institution, it may take up to 10 days for the refund to appear in your account.


If you have received the wrong item, or if your product has been damaged or is defective, please email us with detailed information using the Contact us form, and our Customer Service Manager will address your concern promptly. Do not discard any items unless directed to do so.



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