Chewable Methylated Multivitamin - L-methylfolate + Active B12 - bottle front - 30 Adult Servings - Methyl-Life
Chewable Methylated Multivitamin - L-methylfolate + Active B12 - bottle supplement facts - 30 Adult Servings - Methyl-Life
Chewable Methylated Multivitamin - L-methylfolate + Active B12 - bottle barcode - 30 Adult Servings - Methyl-Life
Chewable Methylated Multivitamin tablets - L-Methylfolate 1 mg + Active B12 - MTHFR/Pregnancy/Children - 30 Adult Servings - Methyl-Life
Chewable Methylated Multivitamin - L-methylfolate + Active B12 - bottle all 3 sides - 30 Adult Servings - Methyl-Life
Chewable Methylated Multivitamin - L-methylfolate + Active B12 - bottle w/tablets - 30 Adult Servings - Methyl-Life

Chewable Methylated Multivitamin - L-Methylfolate 1.3 mg + Active B12 333 mcg - MTHFR/Pregnancy/Children - 30 Adult Servings

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A delicious chewable Methylated Multivitamin with Cognitive & Energy promoting nutrients to support MTHFR and other genetic challenges

Methyl-Life’s® Methylated Multivitamin has a NEW FLAVOR! It's a delicious Sweet 'n Tart Cherry Berry flavored chewable that tastes even better than before (your kids will love it). It holds many of the needed ingredients for methylation to occur optimally in the body. It’s been specially formulated with L-Methylfolate and Active B12 to:
    • Promote glutathione, your body’s strongest antioxidant
    • Boost serotonin, an important neurotransmitter
    • Reduce harmful homocysteine levels in the body
    • Support fertility, pregnancy and fetal health
    • Help repair the myelin sheath for nerve health
    • Support RNA/DNA build blocks
    • Support your thyroid and liver
This formula is BOASTING the PUREST proven L-Methylfolate on the planet, Magnafolate® PRO. This form of L-Methylfolate, is more identical to the pharmaceutical version of methylfolate, AND it tested 3 times more pure in a recent study. Our formula is Gluten, Dairy and Soy free. This multivitamin also contains:
    • The energy-supporting B vitamins along with their co-factors supporting the thyroid
    • Patented Sucrosome® minerals
    • Vitamins A, D3, E and bioactive K2
    • A new ATP energy formula (Panmol® NADH + MicroActive® CoQ10)
    • TMG is built in for lowering homocysteine levels in the body
    • A specialized, soy-free form of choline that crosses the blood brain barrier (Citicoline) for improved cognitive health
    • And another brain health nutrient, soy-free Phosphatidylserine which contains essential phospholipids supporting healthy cognition
    • Artichoke extract and Milk Thistle to support the liver
The Methylated Multi may reduce homocysteine levels in the body. It can be taken along with other Methyl-Life® products that have methylfolate in them (if one wishes to intake higher methylfolate doses). Methyl-Life’s® Methylated Multivitamin is one of the best formulas you’ll find out in the market today. You may find this multi can also act as a nice prenatal without iron or Vitamin C, as well as a great kid’s multi-vitamin (though you’ll want to consider adjusting the number of tablets given as a serving if you take it for these other purposes).

WARNING – How much is right for you to take?

Talk to your doctor about what’s best for you. Check out our dosage information to learn more about what some doctors recommend.


SUGGESTED USE:  Chew 1-4 tablet(s) daily with food (for best absorption), or as directed by your health care professional.
Great for teeth, NOT FOR ANIMALS (contains xylitol).

Serving Size: 4 Chewable Tablets
30 servings per container Amount per Serving % Daily Value

Vitamin A (as Retinyl Palmitate - 2,000 IU)

600 mcg RAE 67%
Vitamin D (as Cholecalciferol [Vitamin D3])
33 mcg (1,333 IU) 165%
Vitamin E (as d-a-Tocopheryl Acid Succinate[Novatol™])
8 mg (121 IU) 53%
Thiamin (Vitamin B1)(as Thiamin HCI) 2 mg 167%
Riboflavin (Vitamin B2)(as Riboflavin 5 Sodium Phosphate) 13 mg 1,000%
Niacin  13 mg NE 81%
Vitamin B6 (as Pyridoxal 5 Phosphate) 3 mg 176%
Folate (as L-5-Methyltetrahydrofolate, Calcium [equal to 1,000 mcg of Magnafolate® PRO]) 1,324 mcg DFE 331%
Vitamin B12 (as Hydroxocobalamin Acetate) 333 mcg 13,875%
Biotin  120 mcg 400%
Pantothenic Acid (as D-Calcium-Pantothenate) 40 mg 800%
Iodine (as Potassium Iodide) 67 mcg 45%
Zinc (as Sucrosomial Zinc Oxide (UltraZin®)) 10 mg 91%
Selenium (as Sucrosomial Sodium Selenite (UltraSel®)) 67 mcg 122%
Manganese (Manganese Bisglycinate Citrate (ALBION)) 2 mg 87%
Chromium (Chromium Nicotinate Glycinate (ALBION)) 23 mcg 66%
Molybdenum (Molybdenum Glycinate(ALBION)) 13 mcg 29%
Artichoke (Leaf) Extract 5% Cynarin  33 mg **
Citicoline Sodium 98% 33 mg **
Coenzyme Q10 25% (MicroActive®) 33 mg **
Phosphatidylserine 20% (from Lecithin)
33 mg **
Milk Thistle (Seed) Extract 80% Silymarin
33 mg **
Trimethylglycine (TMG) 33 mg **
Para-Amino Benzoic Acid (PABA) 17 mg **
Benfotiamine (fat soluble Vitamin B1) 16 mg **
Reduced NADH Complex (9.5% NADH® PANMOL)(NADHMicro) 7 mg **
Vitamin K2 (as Menaquinone-7) 175 mcg **

** Daily Value not established

OTHER INGREDIENTS:  Inositol, Medium Chain Triglycerides, xylitol (Xylisorb®), natural flavors (dextrose, silicon dioxide, citric acid, propylene glycol, sugar, fruit & vege juice & concentrates, phosphoric acid, maltodextrin, potassium bitartrate, calcium lactate),  microcrystalline cellulose (Microcel®), malic acid, sodium stearyl fumarate (PRUV®), monk fruit extract.  Trivial source of calories.

PRODUCT CONTAINS NO: wheat, gluten, dairy, egg, soy, fish, shellfish, yeast, sodium, nuts, caffeine, artificial colorings, preservatives or flavorings, bisphenol-A (BPA), or phthalate.


 What is the right dosage for me?

Check out our Dosage page to learn what some doctors are saying. And consider reviewing our Methylation Protocol page as one example of how someone could start taking the active methylation nutrients.

 Is Methylfolate the only thing I should take if I have an MTHFR gene mutation?

No, actually our recommendation is to heavily consider following Dr. Neil Rawlins’ full supplement protocol. You can learn more about his protocol by watching parts 3 & 4 of his video seminar.

You can also download one of four specific Methylation Protocols which guide you through the beginning nutrients to start. We recommend starting low and slowly titrating up to a dose that works well for you long term. 

You'll find our MTHFR Newbies page is very helpful as well.  It's got some great tips for folks who haven't done much study on what to do if you have an MTHFR variant.

 What do doctors have to say about MTHFR and how to treat it?

Go to A Doctor Explains and listen to Dr. Neil Rawlins’ 51-minute seminar on MTHFR and the effects of Methylfolate.

 How can I get more information on MTHFR?

check out our Help for MTHFR Newbies page.

 Is L-Methylfolate and (6S)-5-Methyltetrahydrofolate, Calcium the same thing?

Basically, yes. In the chemistry world, L stands for the “Left” isomer, which is the same as the “(6S)” isomer – the terms are synonyms (and this naming convention is used interchangeably by various companies in the industry). In the case of methylfolate, that L or (6S) isomer is the active isomer of 5-MTHF that the body can actually use. To learn more about the different types of methylfolate, its history, potency levels and stability details, and to see how our L-Methylfolate proves to be the purest on the planet, visit our Methylfolate Types page.

 What if my blood serum B12 level test comes back as high, does that mean I don’t need B12?

The most important thing to realize is that blood tests for B12 are highly inaccurate at detecting actual cellular levels of B12 (meaning the B12 that’s available for the cells to use). Studies have shown that people can have high or normal B12 levels in the blood and actually show virtually no B12 in the spinal fluid, meaning the B12 is not being transported from the blood stream into the cells where it should be absorbed and used.

 What can you do if you have high B12 blood test results? Dr. Amy Yasko and Nutritionist Cynthia Smith both suggest you can consider taking low dose lithium orotate (Cynthia Smith suggests approximately 4.6 mg pulsed a couple times a week before adding the B12 form in that’s most likely best for you).

 What does sublingual mean and why isn’t your product labeled as “sublingual”?

It’s a well-known fact that B12 does not absorb well through the gut, so taking B12 via sublingual or mouth absorption is best (holding it under the tongue or between the gums and cheek is most common). Consider some form of liquid or tablet/lozenge that can be sucked on or dissolved in the mouth. Holding the B12 in your mouth for at least 90 seconds is good and the longer you can leave it in your mouth, the better for sublingual absorption (as opposed to gut absorption).
Note: different manufacturers use different terms for tablets that are meant to dissolve sublingually in the mouth, but “sublingual” is considered a pharmaceutical term by the FDA, so dietary supplements are moving away from using that term. However, it doesn’t really matter what term you use (chewable tablet, lozenge, sublingual tablet, liquid, etc.) for maximum absorption the main idea is to hold it in your mouth for 90 seconds or more if you can (if you forget, don’t worry, since you’re taking the active form, your body will still get some benefit even if you swallow it whole).

Another way to absorb B12 is muscularly through shots, however, the research tells us that sublingual (or mouth) absorption is equally as effective as muscular absorption … and shots may cost significantly more money. Also, be aware with shots (many doctors still give cyanocobalamin shots) that though you may need higher doses of active B12s (like myself), you may not do well when given higher doses of cyanocobalamin in a shot because your body may not be able to do the conversions and you could have negative side effects.

 My doctor said that because I have MTHFR, I should be taking methylcobalamin as my B12 form, why are you suggesting these other forms too?

One of the most common other nutrients to consider when supplementing the methylation cycle is the proper form of B12. There are 3 different types of B12 that are considered very beneficial to the body (hydroxocobalamin, methylcobalamin or adenosylcobalamin). Many automatically think that if you have an MTHFR defect, then you need the form of B12 called methylcobalamin, but that is simply NOT true.

It’s important to realize that the MTHFR status does not necessarily determine the type of B12 that’s best for you, instead it’s the status of genes like COMT, MTR, MTRR as well as VDR Taq. It is true that methylfolate and methylcobalamin work together synergistically along the methylation cycle pathway, but that doesn’t necessarily mean that if you tolerate methylfolate well you’ll also need, want or tolerate methylcobalamin well (even if that’s what most doctors, nutritionists, etc. are currently saying right now).

It seems there may be a general lack of education available to most doctors about the different forms of B12 and what those forms are as well as how they get converted within the body and what each is most beneficial for (not to mention which set of genes or genetic mutations could benefit most from which B12 type). So do your homework when it comes to B12 to see which you may tolerate best.

The most common form of B12 that you’ll find everywhere is cyanocobalamin and it is not very active or beneficial to the body because the absorption rate is fairly low, that’s because the body has to convert it first into hydroxocobalamin, and from there the hydroxocobalamin has to be converted into both adenosylcobalamin and methylcobalamin. But if the body has genetic mutations then these conversions don’t happen well at all and the effect is the body does not get the absorption or use of the nutrient.

 I have my 23andme test results, how can I use those to know which form of B12 I might best tolerate?

If you have your 23andme genetic test results, you can use those to help guide you as you try the specific B12 forms to see how they do for you. You’ll notice below that, according to Dr. Amy Yasko, the most well tolerated active form of B12 for folks seems to be hydroxocobalamin. Every single one of the genetic combinations she lists below should be able to tolerate B12 in the form of hydroxocobalamin (and this is why our methylation protocol suggests hydroxocobalamin as the B12 form to begin with):

    • Folks with multiple COMT mutations tend to do very well with hydroxocobalamin (it helps mop up excess peroxynitrites which can cause problems)
    • Folks with MTR & MTRR mutations may do well with methylcobalamin & adenosylcobalamin supplementation
    • And Dr. Amy Yasko ( talks about folks with a particular mutation status for COMT & VDR Taq as best needing the below forms of B12:
COMT V158M VDR Taq B12 Types That Should Be Tolerated
– – + + (TT) All 3 types of B12
– – + – (Tt) All 3 types of B12 with less Methylcobalamin
– – – – (tt) Hydroxocobalamin and Adenosylcobalamin
+ – + + All 3 types of B12 with less Methylcobalamin
+ – + – Hydroxocobalamin and Adenosylcobalamin
+ – – – Hydroxocobalamin and Adenosylcobalamin
+ + + + Hydroxocobalamin and Adenosylcobalamin
+ + + – Hydroxocobalamin and Adenosylcobalamin
+ + – – Mostly Hydroxocobalamin

Please Note

Before purchasing any of our products, Methyl-Life® recommends that you talk with a healthcare professional if you have any questions. Methyl-Life® cannot be held liable for adverse reactions or negative side effects that you think are the result of one of our products.

If you have not used Methyl-Life® products before, please consider ordering one bottle to start before making larger orders. We also recommend you read through our dosage and methylation protocol pages and consider starting with a lower dose product to ensure you tolerate the ingredients well before increasing your strength to a higher dose product.

It is also important to speak with your healthcare professional before purchasing. Methyl-Life® prefers not to accept returns for large orders. If you return three unopened bottles from a 4-pack purchase, you will receive a full refund minus the cost of one bottle charged at full price.

Within 45 days of your order, you can return any unopened item shipped to you by Methyl-Life® (as long as all seals are intact). Just let us know you plan to return the product by emailing us at: [email protected] or using the Contact Us form (please include the tracking information so we can be on the lookout for the package).

It will be your responsibility and cost to ensure the return parcel gets to Methyl-Life® (ship to: P.O. Box 33606, Seattle, WA 98133). We suggest you get a tracking number and consider insuring the package. After we receive your returned item, we will process your full refund within 10 business days and send you an email indicating your refund has been complete. Be aware that depending upon your institution, this may not be reflected in your account status for a few days.

If you have received the wrong item or your product has been damaged or is somehow defective, please email us at: [email protected] with detailed information or use the Contact Us form and our Customer Service Manager will address your concern(s) right away. Please do not throw any items away unless or until you are directed to do so.



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