A delicious chewable Methylated Multivitamin with Cognitive & Energy promoting nutrients to support MTHFR and other genetic challenges
L-Methylfolate and Active B12 to:
- Promote glutathione, your body’s strongest antioxidant
- Boost serotonin, an important neurotransmitter
- Reduce harmful homocysteine levels in the body
- Support fertility, pregnancy and fetal health
- Help repair the myelin sheath for nerve health
- Support RNA/DNA build blocks
- Support your thyroid and liver
- The energy-supporting B vitamins along with their co-factors supporting the thyroid
- Patented Sucrosome®
- Vitamins A, D3, E and bioactive K2
- A new ATP energy formula (NADH + CoQ10)
- TMG is built in for lowering homocysteine levels in the body
- A specialized, soy-free form of choline that crosses the blood brain barrier for improved cognitive health
- And another brain health nutrient, soy-free Phosphatidylserine which contains essential phospholipids supporting healthy cognition
- Artichoke extract and Milk Thistle to support the liver
Dosage
WARNING – How much is right for you to take?
Talk to your doctor about what’s best for you. Check out our dosage information to learn more about what some doctors recommend.
SUPPLEMENT FACTS
SUGGESTED USE: Chew 1-4 tablet(s) daily with food (for best absorption), or as directed by your health care professional.
| SUPPLEMENT FACTS | ||
| Serving Size: 4 Chewable Tablets | ||
| 30 servings per container | Amount per Serving | % Daily Value |
|
Calories
|
14 | * |
| Total carbohydrate | 3 g | 1%* |
| Total sugars (including added sugars) | 3 g | 7%* |
|
Vitamin A (as Retinyl Palmitate) |
200 mcg RAE (667 IU) | 22% |
|
Vitamin D (as Cholecalciferol [D3]) |
33 mcg (1,333 IU)
|
165% |
|
Vitamin E (as d-a-Tocopheryl Acid Succinate) |
8 mg (12 IU)
|
53% |
| Thiamin (Vitamin B1)(as Thiamin HCI) | 1 mg | 83% |
| Riboflavin (Vitamin B2)(as Riboflavin 5 Sodium Phosphate) | 6 mg | 462% |
| Niacin | 14 mg NE | 88% |
| Vitamin B6 (as Pyridoxal 5 Phosphate) | 3 mg | 176% |
| Folate (800 mcg L-Methylfolate [from 1 mg of Cerebrofolate®) | 1,360 mcg | 340% |
| Vitamin B12 (as Hydroxy B12 Acetate) | 333 mcg | 13,875% |
| Biotin | 40 mcg | 133% |
| Pantothenic Acid (as D-Calcium-Pantothenate) | 5 mg | 100% |
| Iodine (as Potassium Iodide) | 56 mcg | 37% |
| Zinc (as Liposomal Zinc Oxide) | 12 mg | 109% |
| Selenium (Selenium Glycinate) | 67 mcg | 122% |
| Manganese (Manganese Bisglycinate Citrate) | 2 mg | 87% |
| Chromium (Chromium Nicotinate Glycinate) | 23 mcg | 66% |
| Molybdenum (Molybdenum Glycinate) | 13 mcg | 29% |
| Artichoke (Leaf - Cynara scolymus L.) Extract 5% Cynarin | 33 mg | ** |
| Citicoline Sodium | 33 mg | ** |
| Ubiquinol (CoQ10 Reduced Form) | 10 mg | ** |
|
Phosphatidylserine (Sunflower - Helianthus annuus) |
7 mg | ** |
|
Milk Thistle (Seed - Silybum marianum L.) Extract 80% Silymarin |
33 mg | ** |
| Pantethine | 14 mg | ** |
| Para-Amino Benzoic Acid (PABA) (Vitamin B10) | 7 mg | ** |
| Benfotiamine (Fat Soluble Vitamin B1) | 16 mg | ** |
| NADH (Microencapsulated NADH) | 1 mg | ** |
| Vitamin K2 (as Menaquinone-7) | 68 mcg | ** |
| * Percent Daily Value based on a 2,000 calorie diet | ||
| ** Daily Value not established |
PRODUCT CONTAINS NO: wheat, gluten, dairy, egg, soy, fish, shellfish, yeast, sodium, nuts, caffeine, artificial colorings, preservatives or flavorings, bisphenol-A (BPA), or phthalate.
Research
FAQs
What is the Chewable Methylated Multivitamin?
The Chewable Methylated Multivitamin is a comprehensive multivitamin formula containing L-Methylfolate and Active B12, specifically designed to support individuals with MTHFR mutations, pregnant women, and children.
What are the key features of the Chewable Methylated Multivitamin?
What are the potential benefits of the Methylated Multi?
How can I get more information on MTHFR?
Why is Methyl-Life’s® Methylated Multivitamin considered one of the best formulas available?
What if my blood serum B12 level test comes back as high, does that mean I don’t need B12?
The most important thing to realize is that blood tests for B12 are highly inaccurate at detecting actual cellular levels of B12 (meaning the B12 that’s available for the cells to use). Studies have shown that people can have high or normal B12 levels in the blood and actually show virtually no B12 in the spinal fluid, meaning the B12 is not being transported from the blood stream into the cells where it should be absorbed and used.
How should I use this product?
The suggested use for this product is to chew 1-4 tablets daily with food for optimal absorption. It is recommended to follow the dosage instructions provided by your healthcare professional.
How should I take this for the best results?
My doctor said that because I have MTHFR, I should be taking methylcobalamin as my B12 form, why are you suggesting these other forms too?
One of the most common other nutrients to consider when supplementing the methylation cycle is the proper form of B12. There are 3 different types of B12 that are considered very beneficial to the body (hydroxy B12, methylcobalamin or adenosylcobalamin). Many automatically think that if you have an MTHFR defect, then you need the form of B12 called methylcobalamin, but that is simply NOT true.
It’s important to realize that the MTHFR status does not necessarily determine the type of B12 that’s best for you, instead it’s the status of genes like COMT, MTR, MTRR as well as VDR Taq. It is true that methylfolate and methylcobalamin work together synergistically along the methylation cycle pathway, but that doesn’t necessarily mean that if you tolerate methylfolate well you’ll also need, want or tolerate methylcobalamin well (even if that’s what most doctors, nutritionists, etc. are currently saying right now).
It seems there may be a general lack of education available to most doctors about the different forms of B12 and what those forms are as well as how they get converted within the body and what each is most beneficial for (not to mention which set of genes or genetic mutations could benefit most from which B12 type). So do your homework when it comes to B12 to see which you may tolerate best.
The most common form of B12 that you’ll find everywhere is cyanocobalamin and it is not very active or beneficial to the body because the absorption rate is fairly low, that’s because the body has to convert it first into hydroxy B12, and from there the hydroxy B12 has to be converted into both adenosylcobalamin and methylcobalamin. But if the body has genetic mutations then these conversions don’t happen well at all and the effect is the body does not get the absorption or use of the nutrient.
I have my 23andme test results, how can I use those to know which form of B12 I might best tolerate?
If you have your 23andme genetic test results, you can use those to help guide you as you try the specific B12 forms to see how they do for you. You’ll notice below that, according to Dr. Amy Yasko, the most well tolerated active form of B12 for folks seems to be hydroxy B12. Every single one of the genetic combinations she lists below should be able to tolerate B12 in the form of hydroxy B12 (and this is why our methylation protocol suggests hydroxy B12 as the B12 form to begin with):
- Folks with multiple COMT mutations tend to do very well with hydroxy B12 (it helps mop up excess peroxynitrites which can cause problems)
- Folks with MTR & MTRR mutations may do well with methylcobalamin & adenosylcobalamin supplementation
- And Dr. Amy Yasko (https://dramyyasko.com) talks about folks with a particular mutation status for COMT & VDR Taq as best needing the below forms of B12:
| COMT V158M | VDR Taq | B12 Types That Should Be Tolerated |
|---|---|---|
| – – | + + (TT) | All 3 types of B12 |
| – – | + – (Tt) | All 3 types of B12 with less Methylcobalamin |
| – – | – – (tt) | Hydroxy B12 and Adenosylcobalamin |
| + – | + + | All 3 types of B12 with less Methylcobalamin |
| + – | + – | Hydroxy B12 and Adenosylcobalamin |
| + – | – – | Hydroxy B12 and Adenosylcobalamin |
| + + | + + | Hydroxy B12 and Adenosylcobalamin |
| + + | + – | Hydroxy B12 and Adenosylcobalamin |
| + + | – – | Mostly Hydroxy B12 |
