B12 Forms Ideal for Specific COMT and VDR Taq Genetics

Check out the chart below and match your genetic mutation status for each SNP (single nucleotide polymorphism) to determine what B12 form(s) are best for you personally, according to Dr. Amy Yasko.

Consider taking bioidentical B12 forms in conjunction with L-Methylfolate because they work synergistically together in the body on the methylation pathway and can amplify its benefits. Stay AWAY from cyanocobalamin in supplements and fortified foods! Methyl-Life® carries affordable, vegan versions of active B12 in a tasty sublingual tablet (some products even include L-Methylfolate).

Bioidentical Active B12 Forms:

• Hydroxocobalamin - harder to find, expensive, typically well-tolerated and used for pernicious anemia among other things
• Methylcobalamin - fairly available and found in some supplements. Note: it's not always well tolerated
• Adenosylcobalamin - harder to find, expensive, the most well-tolerated and often used in muscle recovery

B12 does NOT absorb well via the gut, so be sure to get a product that allows you to dissolve the B12 under your tongue. Sublingual transport is the best way to get B12 absorption (research has proven it's even better than B12 injections for increasing B12 sufficiency). If B12 blood serum levels test "high", consider Methyl-Life®'s Non-Methylated Multivitamin.

Learn more about the best bioidentical B12 forms to take.