Third-Party Tested
Every batch, not just some — verified for purity and potency.
Ultra-Pure Methylfolate
Formulated with the cleanest, most bioavailable L-Methylfolate.
NSF Certified & FDA Registered
Manufactured in a facility that exceeds quality standards.
Top 14 Allergen Free
Without any of the EU’s top 14 allergens — clean and worry-free supplementation.
Made in the USA
Ensuring trusted quality and ingredient traceability.
Shop by Category
MTHFR Supplements
MTHFR Supplements from Methyl-Life® provide targeted nutritional support for those mindful of their methylation health.
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L-Methylfolate
L-Methylfolate is the active, bioavailable form of folate that supports healthy methylation, neurotransmitter production, and cellular function.
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B12 Supplements
Our B12 Supplements include bioavailable forms designed to support red blood cell production, healthy nervous system function, and energy metabolism.
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Methyl-B12
Methyl-B12 supplements offer bioactive methylcobalamin to help maintain healthy nerve function, support energy production, and promote mental clarity.
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Methylated Vitamins
Our Methylated Vitamins combine active forms of folate and B12 with essential cofactors to support energy metabolism, cognitive clarity, and overall wellness.
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Superior Magnesium
Discover magnesium supplements with advanced bioavailability, formulated for efficient absorption and optimal effectiveness.
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What Makes Methyl-Life®’s Manufacturing Process Exceptional?
Made in the USA (NSF Certified Manufacturer)
All Methyl-Life® supplements are produced in an FDA-registered, cGMP-compliant facility, and we go a step further with NSF Certification, the gold standard for supplement quality.
Transparent + Traceable Ingredients
Each product comes with a Certificate of Analysis (COA). Want to verify? Just ask. We believe you deserve to know exactly what you're putting in your body.
Founder-Led Quality Commitment
Our founder, Jamie Hope, lives with the same methylation challenges as many of our customers. That’s why our motto is simple: “We take our own medicine.”
Third-Party Tested - Every. Single. Batch.
Unlike most brands that only spot-check, we third-party test every single batch for potency and purity, so you always get what the label promises.
Shop by Health Goal
Support Pregnancy & Fertility
Bioavailable folate and B12 to support your body’s natural rhythms during preconception and pregnancy - especially important if you're managing MTHFR.
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Support Cognition & Immune Health
Methylated folate and B12 to help support brain and immune system function - ideal for those navigating high-stress or wellness-focused lifestyles.
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Step-by-Step Nutrient Support for Kids
A simplified guide for parents managing MTHFR or methylation issues in children. These formulas offer age-appropriate support for mood, focus, immunity, and developmental wellness — backed by expert dosing insights.
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Cardiovascular & Nerve Health Support
These nutrients help regulate homocysteine, blood sugar metabolism, red blood cell production, and nerve signaling. A foundational choice for those managing cardiovascular risk, diabetes, anemia, or nerve-related issues.
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Explore Our Best Active B12 Supplements
Methyl-Life® offers methylcobalamin, hydroxocobalamin, and adenosylcobalamin — the most effective B12 forms for absorption and impact. Designed to bypass genetic blocks for optimal cellular support.
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Targeted Support for Gut Health
Methylation plays a vital role in gut lining integrity, immune regulation, and detox. These formulas promote optimal digestion, healthy flora, and support for those with MTHFR or gut-related fatigue.
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Let customers speak for us
Trusted Methylated Supplements Backed by Science & Personal Experience
Founded by Jamie Hope. Formulated for People Who Need Real Results.
At Methyl-Life®, we believe nutritional support should go beyond generic formulas and vague health promises. That’s why we specialize in methylated supplements — high-quality, bioavailable nutrients designed for those who need targeted support for methylation, mental health, cardiovascular health, pregnancy, energy levels, and more.
Our flagship products, including L-Methylfolate and methylated B vitamins, are meticulously formulated to deliver therapeutic-grade support for people with MTHFR gene mutations, nutrient absorption issues, or increased neurological, immune, or metabolic needs.
Why Methylation Matters
Methylation is a key biochemical process that affects everything from your mood and DNA to detoxification and cardiovascular health.
