The Benefits and Importance of B12 During Pregnancy
Vitamin B121 is a water-soluble vitamin required at every stage in life, most critically during pregnancy.
B12 plays a crucial role in DNA synthesis, methylation reactions, and maintenance of genomic stability. During pregnancy, it is particularly necessary for neural myelination, cognitive function, red blood cell formation, and the development of the central nervous system.
Low B12 status is common in pregnant mothers,2 particularly in resource-poor environments and in multiple pregnancies. Tissue stores of B12 are depleted, leading to impairments in B12-dependent pathways3 and, subsequently, increased levels of homocysteine and methylmalonic acid.
Brain development begins from conception, and pregnancy is a period of rapid growth and development for the child’s brain. Poor vitamin B12 status4 during pregnancy and infancy has been linked to harmful effects5 on the fetus, including poor neurodevelopment, low birth weight, and a higher risk of neural tube defects.
This article will discuss the importance of B12 during pregnancy and its many benefits for both the mother and the developing fetus. We will explain how to identify a B12 deficiency and how to support B12 levels through diet and supplementation during pregnancy.
