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High Histamine food list Browse Categories B-12 COVID-19 Deficiencies  Fertility / Pregnancy / Women's Health  Health Issues  Kid's Health Mental Health  Methylfolate Facts  MTHFR Genetics  News  Resources  Staying Healthy  Super-B-Complex 1. Histamine and its physiological functions Histamine is a type of biogenic tissue amine – L-histidine decarboxylase (HDC) and the cofactor pyridoxal 5’-phosphate or the active form of vitamin B6 mediate the conversion of histidine into histamine (its chemical reaction is represented in figure 1). The key enzymes such as diamine oxidase (DAO) and histamine N-methyltransferase (HNMT) degrade histamine into different by-products. Figure1. Biosynthesis of Histamine from L-histidine. As perthe International Union of Pure and Applied Chemistry (IUPAC)nomenclature, the chemical name of histamine is 2-(1H-imidazol-4-yl)ethanamine. Essentially, the biogenic amines such as histamine,...
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