Breast cancer is one of the most common forms of cancer worldwide and the second leading cause of cancer-related death among women after lung cancer.1 Although every woman is at some risk for breast cancer, the degree of risk for individual women can vary considerably.
Research suggests that genes are the strongest hereditary risk factor for developing breast cancer, particularly in women who are affected at a younger age. In fact, around 10–20% of early-onset cases are hereditary.2
For this reason, women with a family history of breast cancer are strongly advised to be aware of their higher risks and seek regular checkups.
This article will discuss the role of genetic factors in breast cancer, including the potential for the MTHFR gene to play a part. We will also cover how to manage your risks and support your health if you are affected by certain gene variants.