How Does MTHFR Affect Weight Gain
Many of us have, at some stage in our lives, tried to lose weight. Not all of us are successful. For some, it’s a matter of diet and exercise; others can blame stress or medical conditions. But some people may never figure out why they can’t shed those pounds, even when they’re eating well and working out.
For those people, genes could be to blame. Specifically, the MTHFR gene. But how can an MTHFR mutation affect weight?
Recent research has suggested that an MTHFR mutation may affect metabolism to the point where weight loss is much more difficult.
MTHFR genetic mutations have been linked to both weight gain or ineffective weight loss efforts. This may be due to nutritional deficiencies that result from poor methylation in the body. Methylation is required for numerous metabolic processes and has been implicated in weight gain and obesity1.
Fortunately, many people have found that weight loss becomes easier after supporting their bodies with the nutrients their MTHFR mutation has otherwise depleted.
This article will outline the role of the MTHFR gene in weight maintenance and how a mutated gene may lead to weight gain. We’ll also explain how estrogen affects body weight and how estrogen clearance may be affected by a MTHFR polymorphism.
We can then look at how those with an MTHFR polymorphism can manage a healthy weight and support weight loss through diet and supplements.
